Protein Alignment Frmd5 and cora

DIOPT Version :10

• Sequence 1: NP_609384.1
• Gene: Frmd5 / 34398
• FlyBaseID: FBgn0032225
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_523791.2
• Gene: cora / 37205
• FlyBaseID: FBgn0010434
• Length: 1698
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 155/587 - (26%)
• Similarity: 236/587 - (40%)
• Gaps: 137/587 - (23%)

  Fly    16 VRLLDDSDVLECEFQPFHKGIYLLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSKSIIKQCK- 79
            |.|||.| :|:........|..::..:|..|.:.|||||||.|...:..|.||||.|.:.|..:
  Fly    36 VTLLDGS-LLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRT 99

  Fly    80 EMDPLLFSLRVKFYPADPFRLTGN-ARIMLYQQLKRDLRHGRLYCSLGEAAALGALIVQEELGDY 143
            :..||.|:  |||||.:|.:|..: .|..|..|::.|:..|||.|:....|.||:.:||.|:|||
  Fly   100 DTWPLTFA--VKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDY 162

  Fly   144 N-EDVHVGSYVSSIELALRQTECLEKKIIELHKKREPGQNLSLAMDEFLGIARGLETYGIDPHPV 207
            : |::...:|:...::|..||..||.|:::|||..: ||:.:.|...:|..|:.|..||:|.||.
  Fly   163 DAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHK-GQSPAEAELHYLENAKKLAMYGVDLHPA 226

  Fly   208 KDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEGKMFIAHLSYTDASREPKKHTVGFK 272
            ||..|....:|:..:|:..:....|...|.|.:|.||:::...|  ::.......|..:.|:|||
  Fly   227 KDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHF--YIKIRPGEFEQYESTIGFK 289

  Fly   273 CPTGAACRYLWRCAIEQMLFFTL----PNSQSAAVISGGGFFSWGTKFRYTGRTEREILTENINA 333
            .....|.:.||:..:|...||.|    |.|:|..      |..:|:.:||.|||:.|.....::.
  Fly   290 LANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKM------FPVFGSTYRYKGRTQAESTNTPVDR 348

  Fly   334 LREQKNNSNSSKRKAS-SVPATPSSPQGDLAQIRYSSLPRSTMSEPLGYGMPNGHFYGHDHGMSD 397
            ...:.|.:.|..|..| |:.|..      ||:....:...||:                || ..|
  Fly   349 TPPKFNRTLSGARLTSRSMDALA------LAEKEKVARKSSTL----------------DH-RGD 390

  Fly   398 ANGGIQISSLEPV--------CEEARLR------------------------------------- 417
            .|......|..|:        .:||:||
  Fly   391 RNADGDAHSRSPIKNKKEKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAG 455

  Fly   418 ---------------------SSNIDGVNYLAS---QIGGYAYRDSVEHSSTE------------ 446
                                 ||...||...:|   ...|...:|..:.|..:
  Fly   456 AAAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVV 520

  Fly   447 -SGLTVNGYDH---PRKHNEARQHGSYSPNL-----YYGQSDGAVN----SSSPADSFLHADPST 498
             |||..|..|.   ....|.|:..||.:|.:     |...:||..:    |.:|.......||::
  Fly   521 TSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNS 585

  Fly   499 RK 500
            ||
  Fly   586 RK 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frmd5	NP_609384.1	FERM_F1_FRMD3	12..93	CDD:340622	29/77 (38%)
		FERM_M	104..205	CDD:459788	37/101 (37%)
		FERM_C_FRMD3_FRMD5	186..294	CDD:270013	31/107 (29%)
		FA	308..350	CDD:462582	12/42 (29%)
cora	NP_523791.2	B41	34..224	CDD:214604	71/191 (37%)
		FERM_C_4_1_family	219..312	CDD:270005	28/94 (30%)
		FA	324..364	CDD:462582	11/39 (28%)
		4_1_CTD	1613..1698	CDD:461774