DRSC/TRiP Functional Genomics Resources

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Protein Alignment Frmd5 and epb41b

DIOPT Version :10

Sequence 1:NP_609384.1 Gene:Frmd5 / 34398 FlyBaseID:FBgn0032225 Length:572 Species:Drosophila melanogaster
Sequence 2:NP_778259.1 Gene:epb41b / 326287 ZFINID:ZDB-GENE-030130-1 Length:1534 Species:Danio rerio


Alignment Length:398 Identity:127/398 - (31%)
Similarity:193/398 - (48%) Gaps:41/398 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 KCTVRLLDDSDVLECEFQPFHKGIYLLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSKSIIKQ 77
            :|.|..|||: :...|.:....|..|...:|..|.:.|:|||||...||...|.|||.:|.|.||
Zfish     3 QCRVNFLDDT-LFTWELERDSLGQDLFNKVCEHLNLLERDYFGLVMWDSPTNRVWLDCAKEIRKQ 66

  Fly    78 CKEMDPLL-FSLRVKFYPADPFRLTGN-ARIMLYQQLKRDLRHGRLYCSLGEAAALGALIVQEEL 140
            .|  .|:. |...:||||.||..|..: .|..|...|::|:..|||.|.....|.||:..||..|
Zfish    67 IK--SPVAEFFFSIKFYPPDPSILAEDITRYFLCLHLRKDILIGRLPCPSDILALLGSYTVQSTL 129

  Fly   141 GDYNEDVHVGSYVSSIELALRQTECLEKKIIELH---KKREPGQNLSLAMDEFLGIARGLETYGI 202
            |||:.::|..:||..|.||..|::.||:|::|||   :...|.|...|    ||....||..||:
Zfish   130 GDYDPNLHKNNYVRKIVLAPNQSKELEEKVMELHATYRFMSPAQADLL----FLENVMGLPMYGV 190

  Fly   203 DPHPVKDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEGKMFIAHL--SYTDASREPK 265
            |.||.||..|....:|:.:.|:..:..|.::..|.|..:.||:.:...|:..:  |..|||    
Zfish   191 DLHPAKDASGEDVMLGVCSEGLIVYEDGVKTNSFFWPRVLKISHKRNTFLLKMRPSEEDAS---- 251

  Fly   266 KHTVGFKCPTGAACRYLWRCAIEQMLFF--TLPNSQSAAVISGGGFFSWGTKFRYTGRTEREILT 328
            :..:.|......||:.||:|::|...||  .|.::::..::      :.|::|||.||.:.|.:.
Zfish   252 EGNLSFSLANYRACKQLWKCSVEHHSFFRNRLQDTKAKRLL------TLGSRFRYHGRKQSECVE 310

  Fly   329 ENINALREQKNNSN-SSKRKASSVPATPSSPQGDLAQIRYSSLP-RSTMSE-PLGYGMPNGHFYG 390
            .:.|..|.....:. |.||||:.          ::..:  ..|| |:.:.: .|.||....|.|.
Zfish   311 ASSNITRAPPRFTRYSIKRKANE----------EILDV--LKLPVRAEVDDWFLVYGPEKWHIYT 363

  Fly   391 HDHGMSDA 398
            .|..|.::
Zfish   364 SDDVMLES 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Frmd5NP_609384.1 FERM_F1_FRMD3 12..93 CDD:340622 30/80 (38%)
FERM_M 104..205 CDD:459788 40/103 (39%)
FERM_C_FRMD3_FRMD5 186..294 CDD:270013 33/111 (30%)
FA 308..350 CDD:462582 14/42 (33%)
epb41bNP_778259.1 Ubl1_cv_Nsp3_N-like 2..84 CDD:475130 33/83 (40%)
B41 4..193 CDD:214604 76/195 (39%)
FERM_C_4_1_family 188..281 CDD:270005 29/96 (30%)
FA 290..331 CDD:462582 12/46 (26%)
SAB 1451..1498 CDD:461285
Blue background indicates that the domain is not in the aligned region.

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