Protein Alignment CG5022 and Frmd6

DIOPT Version :9

• Sequence 1: NP_609384.1
• Gene: CG5022 / 34398
• FlyBaseID: FBgn0032225
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_082403.2
• Gene: Frmd6 / 319710
• MGIID: 2442579
• Length: 622
• Species: Mus musculus
• Alignment Length: 502
• Identity: 107/502 - (21%)
• Similarity: 184/502 - (36%)
• Gaps: 127/502 - (25%)

  Fly    27 CEFQPFHKGI-----------YLLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSKSIIKQC-- 78
            |.|.|..|.:           .||..:|..|.:|:...|||..:.:: :..:::||:.:.|.|
Mouse    19 CIFLPNDKSVSIIINVKILCHQLLVQVCDLLRLKDSHLFGLSVIQNN-EHVYMELSQKLYKYCPK 82

  Fly    79 ---KEMD----------------PLLFSLRVKFYPADPFRLTGN-ARIMLYQQLKRDLRHGRLYC 123
               ||..                |::...||::|..:...::.. ||...|..|::.:.|.:  |
Mouse    83 EWKKEASKVRQYEVTWGIDQFGPPMIIHFRVQYYVENGKLISDRIARYYYYWHLRKQVLHSQ--C 145

  Fly   124 SLGEAA--ALGALIVQEELGDYNEDVHVG------SYVSSIELALRQTECLEKKIIELHKKREPG 180
            .|.|.|  .|.|..:|.:||::...:|.|      :|..:..::.|..:.:.|.|..:||
Mouse   146 VLREEAYFLLAAFALQADLGNFKRKLHHGDYFEPEAYFPAWVVSKRGKDYILKHIPNMHK----- 205

  Fly   181 QNLSLAMDE----FLGIARGLETYGIDPHPV-KDHRGSQ--QYVGINNTGISTFVAGKRSQH--- 235
            ...:|...|    ::..|..|:...|..:.: ||.|.::  ..:|:...||..|...:..:.
Mouse   206 DQFALTASEAYLKYIKEAVRLDDVAIHYYRLYKDKREAEGSLTLGLTMRGIQIFQNLEEEKQLLY 270

  Fly   236 -FRWNEIHKINFEGKMFIAHLSYTDASREPKKHTVGFKCPTGAACRYLWRCAIEQMLFFTLPNSQ 299
             |.|..:.|:.|.||.|..   ..|.....:|......|||.:  |:|.:         .|.||.
Mouse   271 DFPWTNVGKLVFVGKKFEI---LPDGLPSARKLVYYTGCPTRS--RHLLQ---------LLSNSH 321

  Fly   300 SAAVISGGGFFSWGTKFRYTGRTE--------RE-ILTENI----NALREQKNNSNSS----KRK 347
            ..       :.:.....|:..:.|        || .:::|:    :.|.::...|.||    |.|
Mouse   322 RL-------YMNLQPVLRHLRKQEENEEKKQYRESYISDNLDLDMDPLEKRSRASGSSAGSVKHK 379

  Fly   348 ASSVPATPSSPQGDLAQIRYSSLPRSTMSEPLGYGMPNGHFYGHDHGMSDANGGIQISSLEPVCE 412
            ..|..:|.|......:.|...:.||                   |.|..|:..|..:......|.
Mouse   380 RLSRHSTASHSSSHTSGIEADTKPR-------------------DPGPEDSCSGSAMHRKLKTCS 425

  Fly   413 EARLR-SSNIDGVNYLASQIGGYAYRDSVEHSSTESGLTVNGYDHPR 458
            ..... ||:..||     :.||   :|.:|..|.:..:.:. .|.||
Mouse   426 SMTSHGSSHTSGV-----ESGG---KDRLEEDSQDEEIEML-VDDPR 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5022	NP_609384.1	B41	13..205	CDD:214604	49/222 (22%)
		FERM_N	16..80	CDD:286467	16/68 (24%)
		FERM_M	108..205	CDD:278785	25/108 (23%)
		FERM_C_FRMD3_FRMD5	186..294	CDD:270013	25/118 (21%)
		FA	308..349	CDD:285894	11/57 (19%)
Frmd6	NP_082403.2	Ubiquitin_like_fold	15..120	CDD:421700	22/101 (22%)
		FERM_M	123..234	CDD:395297	27/117 (23%)
		FERM_C_FRMD1_FRMD6	227..335	CDD:270006	26/128 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	357..452		26/121 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841768
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930