DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5022 and CG12075

DIOPT Version :9

Sequence 1:	NP_609384.1	Gene:	CG5022 / 34398	FlyBaseID:	FBgn0032225	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001245582.1	Gene:	CG12075 / 31815	FlyBaseID:	FBgn0030065	Length:	1006	Species:	Drosophila melanogaster

Alignment Length:	254	Identity:	58/254 - (22%)
Similarity:	85/254 - (33%)	Gaps:	50/254 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 DASR--EPKKHTV-----GFKCPTGAACRYLWRCAIEQMLFFTLPNSQSAAVISGGGFFSWGTK- 315
            |.||  ||.|.|:     |.|...||:...:...||...:   ..:...|.|:.   .::..||
  Fly    42 DRSRGQEPLKVTLQVSHKGIKIVQGASKHLIPHSAITSSV---QTDDIVACVLL---LYNPATKC 100

  Fly   316 ------FRYTGRTEREILTENINALREQKNNSNSSKRKASSVPATPSSPQGDLAQIRYSSLPRST 374
                  :|....|..|.|...:..|..:.:|....:...:.:...|..|.....:.|:.|..:|:
  Fly   101 PLHVHAYRCDSETTAEALHLQLQILINRPDNQKRFEELETRLGILPPIPMNGSNEKRHESNGKSS 165

  Fly   375 MSEPLGYGMPNGHFYGHDHGM-SDANGGIQISSLEPVCEEARLRSSNIDGVNYLASQIGGYAYRD 438
            .|...|   |..|   |.|.: |..:||.:...........|..||       |.|..|. :.|:
  Fly   166 SSGGTG---PGSH---HHHQLQSQTSGGYREGRRHETSSPKRFSSS-------LGSDTGN-STRE 216

  Fly   439 SVEHSSTESGLTV-------------NGYDHPRKHNEARQHGSYSPNLYYGQSDGAVNS 484
            |  ..|.|.||..             |...||..|.....|..:.|.|...|:....:|
  Fly   217 S--ECSEEHGLVAGGSSPVSRSPPHGNSKSHPHAHPHHPPHSLHHPPLTPQQNSDLFDS 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5022	NP_609384.1	B41	13..205	CDD:214604
		FERM_N	16..80	CDD:286467
		FERM_M	108..205	CDD:278785
		FERM_C_FRMD3_FRMD5	186..294	CDD:270013	13/41 (32%)
		FA	308..349	CDD:285894	8/47 (17%)
CG12075	NP_001245582.1	PTB	12..120	CDD:269911	21/83 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3530
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900