DRSC/TRiP Functional Genomics Resources

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Protein Alignment Frmd5 and Epb41

DIOPT Version :10

Sequence 1:NP_609384.1 Gene:Frmd5 / 34398 FlyBaseID:FBgn0032225 Length:572 Species:Drosophila melanogaster
Sequence 2:XP_017449316.1 Gene:Epb41 / 313052 RGDID:1564762 Length:1020 Species:Rattus norvegicus


Alignment Length:385 Identity:139/385 - (36%)
Similarity:203/385 - (52%) Gaps:34/385 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 CTVRLLDDSDVLECEFQPFHKGIYLLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSKSIIKQC 78
            |.|.||||: |.||..:...||..||:.:|..|.:.|:|||||...||:..:.|||.:|.|.||.
  Rat   211 CKVSLLDDT-VYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAVWDSTTSKTWLDSAKEIKKQV 274

  Fly    79 KEMDPLLFSLRVKFYPADPFRLTGN-ARIMLYQQLKRDLRHGRLYCSLGEAAALGALIVQEELGD 142
            :.: |..|:..|||||.||.:||.: .|..|..||::|:..|||.||....|.||:..||.||||
  Rat   275 RGV-PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTVQSELGD 338

  Fly   143 YNEDVHVGSYVSSIELALRQTECLEKKIIELHK---KREPGQNLSLAMDEFLGIARGLETYGIDP 204
            |:.::|...|||..:||..||..||:|::||||   ...|.|    |..|||..|:.|..||:|.
  Rat   339 YDPELHGVDYVSDFKLAPNQTRELEEKVMELHKSYRSMTPAQ----ADLEFLENAKKLSMYGVDL 399

  Fly   205 HPVKDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEGKMFIAHLSYTDASREPKKHTV 269
            |..||..|....:|:.::|:..:....|...|.|.::.||:::...|.  :......:|..:.|:
  Rat   400 HKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFF--IKIRPGEQEHYESTI 462

  Fly   270 GFKCPTGAACRYLWRCAIEQMLFF------TLPNSQSAAVISGGGFFSWGTKFRYTGRTEREILT 328
            |||.|:..|.:.||:..:|...||      |||.|:         |.:.|:||||:|||:.:  |
  Rat   463 GFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTLPKSK---------FLALGSKFRYSGRTQAQ--T 516

  Fly   329 ENINALREQKN---NSNSSKRKASSVPATPSSPQGDLAQIRYSSLPRSTMSEPL-GYGMP 384
            ...:||.::..   ...:|||.:.|:....::...|.:. |.:|.|....|:.: |.|.|
  Rat   517 RQASALIDRPAPHFERTASKRASRSLDGAAAAESTDRSP-RPTSAPAIAQSQVMEGPGAP 575

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Frmd5NP_609384.1 FERM_F1_FRMD3 12..93 CDD:340622 34/78 (44%)
FERM_M 104..205 CDD:459788 46/103 (45%)
FERM_C_FRMD3_FRMD5 186..294 CDD:270013 33/113 (29%)
FA 308..350 CDD:462582 15/44 (34%)
Epb41XP_017449316.1 B41 210..400 CDD:214604 87/194 (45%)
FERM_C_4_1_family 395..488 CDD:270005 27/94 (29%)
FA 498..541 CDD:462582 15/53 (28%)
SAB 658..706 CDD:461285
4_1_CTD 909..1016 CDD:461774
Blue background indicates that the domain is not in the aligned region.

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