Protein Alignment Frmd5 and Epb41l4a

DIOPT Version :10

• Sequence 1: NP_609384.1
• Gene: Frmd5 / 34398
• FlyBaseID: FBgn0032225
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001100867.2
• Gene: Epb41l4a / 307514
• RGDID: 1306034
• Length: 688
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 143/530 - (26%)
• Similarity: 230/530 - (43%)
• Gaps: 77/530 - (14%)

  Fly    12 YKCTVRLLDDSDV-LECEFQPFH---KGIYLLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSK 72
            :.|.|.|||:|.: |..:.|...   ||..:|:::...:.:.|.|||||||.|.|.|.:|||.:|
  Rat    11 FYCEVLLLDESKLTLTTQHQGIKKSTKGSVVLDHVFRHVNLVEIDYFGLRYCDRSHQTYWLDPAK 75

  Fly    73 SIIKQCKEM----DPLLFSLRVKFYPADPFRLTGN-ARIMLYQQLKRDLRHGRLYCSLGEAAALG 132
            ::.:. ||:    .|......:|||..||.:|... .|...:.|:|:|...|||.|.:..||.||
  Rat    76 TLAEH-KELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDALQGRLPCPVNIAAQLG 139

  Fly   133 ALIVQEELGDYNEDVHVGSYVSSIELALRQTECLEKKIIELHKKREPGQNLSLAMDEFLGIARGL 197
            |..:|.||||::...|...|||.......|.|.||:.|..:||.. .||..|.|...:|..|:.|
  Rat   140 AYAIQAELGDHDPCKHTAGYVSEYRFVPDQKEELEESIERIHKTL-MGQAPSEAELNYLRTAKSL 203

  Fly   198 ETYGIDPHPVKDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEGKMFIAHLSYTDASR 262
            |.||:|.|||.....|:.::|:...|:..:...|:...:.|..|.|::|:...|...:...|.:
  Rat   204 EMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHFKETQFELRVLGKDCN- 267

  Fly   263 EPKKHTVGFKCPTGAACRYLWRCAIEQMLFFTLPNSQSAAV---ISGGGFFSWGTKFRYTGRTER 324
               :.:..|:..:..||::||:|::|...||.:|.::|.::   :|..|..|:  |.||:|||..
  Rat   268 ---ETSFFFEARSKTACKHLWKCSVEHHTFFRMPETESNSLSRKLSKFGSISY--KHRYSGRTAL 327

  Fly   325 EILTENINALREQKNNSNSSKRKASSVPATPSSPQGDLAQIRYSSLPRSTMSEPLGYGMPNGHFY 389
            ::..:....|.....|...|:.|........:.|.|.      :|:.|.|.:      :.||
  Rat   328 QMSRDLSIQLPRPNQNVVRSRSKTYPKRVAQTQPAGS------NSINRMTAN------LENG--- 377

  Fly   390 GHDHGMSDANGGIQISSLEPVCEEARLRSSNIDGVNYLASQIGGYAYRDSVEHSSTESGL----- 449
                   :..|..:|.:..||....:.::.|........|..       ..|.:..:|||
  Rat   378 -------ENEGTTKIIAPSPVKSFKKAKNENSPDPQRSKSHA-------PWEENGPQSGLYNSPS 428

  Fly   450 -------------------TVNGYDHPRKHNEARQHGSYSPNLYYGQSDGAVNSSSPADSFLHAD 495
                               :.|....|.:..:|...|..|......:|....|:||.::|    :
  Rat   429 DRTKSPKFPCTRQRNLSCGSDNDSSQPMRRRKAHHSGEDSDLKQRRRSRSRCNTSSGSES----E 489

  Fly   496 PSTRKVKKFR 505
            .|.|:.:|.|
  Rat   490 NSNREHRKKR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Frmd5	NP_609384.1	FERM_F1_FRMD3	12..93	CDD:340622	30/88 (34%)
		FERM_M	104..205	CDD:459788	40/100 (40%)
		FERM_C_FRMD3_FRMD5	186..294	CDD:270013	29/107 (27%)
		FA	308..350	CDD:462582	12/41 (29%)
Epb41l4a	NP_001100867.2	None