Protein Alignment CG5022 and FRMD6

DIOPT Version :9

• Sequence 1: NP_609384.1
• Gene: CG5022 / 34398
• FlyBaseID: FBgn0032225
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001253975.1
• Gene: FRMD6 / 122786
• HGNCID: 19839
• Length: 622
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 99/516 - (19%)
• Similarity: 167/516 - (32%)
• Gaps: 185/516 - (35%)

  Fly    38 LLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSKSIIKQC-----KEMD--------------- 82
            ||..:|..|.:|:...|||..:.:: :..:::||:.:.|.|     ||..
Human    41 LLVQVCDLLRLKDCHLFGLSVIQNN-EHVYMELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFG 104

  Fly    83 -PLLFSLRVKFYPADPFRLTGN--ARIMLYQQLKRDLRHGRLYCSLGEAA--ALGALIVQEELGD 142
             |::...||::| .:..||..:  ||...|..|::.:.|.:  |.|.|.|  .|.|..:|.:||:
Human   105 PPMIIHFRVQYY-VENGRLISDRAARYYYYWHLRKQVLHSQ--CVLREEAYFLLAAFALQADLGN 166

  Fly   143 YNEDVHVG------SYVSSIELALRQTECLEKKIIELHKKREPGQNLSLAMDE----FLGIARGL 197
            :..:.|.|      :|..|..::.|..:.:.|.|..:||     ...:|...|    ::..|..|
Human   167 FKRNKHYGKYFEPEAYFPSWVVSKRGKDYILKHIPNMHK-----DQFALTASEAHLKYIKEAVRL 226

  Fly   198 ETYGIDPHPV-KDHR--GSQQYVGINNTGISTFVAGKRSQH----FRWNEIHKINFEGKMFIAHL 255
            :...:..:.: ||.|  .:...:|:...||..|......:.    |.|..:.|:.|.||.|
Human   227 DDVAVHYYRLYKDKREIEASLTLGLTMRGIQIFQNLDEEKQLLYDFPWTNVGKLVFVGKKF---- 287

  Fly   256 SYTDASREPKKHTVGFKCPTGAACRYLWRCAIEQMLFFTLPNSQSAAVISGGGFFSWGTKFRYTG 320
                                                                             
Human   288 ----------------------------------------------------------------- 287

  Fly   321 RTEREILTENINALREQKNNSNSSKRKASSVPATPSSPQGDLAQIRYSSLPRSTMSEPLGYGMPN 385
                |||.:.:.:.|:                           .|.|:..|  ..|..|...:.|
Human   288 ----EILPDGLPSARK---------------------------LIYYTGCP--MRSRHLLQLLSN 319

  Fly   386 GH-FYGHDHGMSDANGGIQISSLEPVCEEARLRSSNIDGVNYLASQIGGY--AYRDSVEHSSTES 447
            .| .|               .:|:||....|....|.:...|..|.|...  ...|.:|..|..|
Human   320 SHRLY---------------MNLQPVLRHIRKLEENEEKKQYRESYISDNLDLDMDQLEKRSRAS 369

  Fly   448 GLTVNGYDHPR--KHNEARQHGSYSPNLYYGQSDGAVNSSSPADSF----LHADPSTRKVK 502
            |.:.....|.|  :|:.|....|::..:   ::|.....:.|.||:    :|     ||:|
Human   370 GSSAGSMKHKRLSRHSTASHSSSHTSGI---EADTKPRDTGPEDSYSSSAIH-----RKLK 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5022	NP_609384.1	B41	13..205	CDD:214604	47/201 (23%)
		FERM_N	16..80	CDD:286467	12/46 (26%)
		FERM_M	108..205	CDD:278785	25/108 (23%)
		FERM_C_FRMD3_FRMD5	186..294	CDD:270013	17/118 (14%)
		FA	308..349	CDD:285894	4/40 (10%)
FRMD6	NP_001253975.1	FERM_F1_FRMD6	15..120	CDD:340718	18/80 (23%)
		FERM_B-lobe	128..226	CDD:271216	26/104 (25%)
		FERM_C_FRMD1_FRMD6	227..335	CDD:270006	29/224 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..445		16/67 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151649
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840