DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5022 and nploc4

DIOPT Version :9

Sequence 1:	NP_609384.1	Gene:	CG5022 / 34398	FlyBaseID:	FBgn0032225	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001135712.1	Gene:	nploc4 / 100216289	XenbaseID:	XB-GENE-958208	Length:	610	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	68/316 - (21%)
Similarity:	100/316 - (31%)	Gaps:	113/316 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FRSKNEGNIVYKCTVRLLDDSDVLECEFQPFHKGIYLLEYLCGELEIKEKDYFGLRYVDS----- 61
            :.||.:|.| |:       :.|...|...|..|.::     |..||..::||  |.::|.
Frog   115 YLSKQDGKI-YR-------NRDPQLCRHGPLGKCVH-----CVPLEPFDEDY--LNHLDPPVKHM 164

  Fly    62 ------SKQRHWLDLSKSI--------IKQ------------CKEMDPLLFSLRVKFYP------ 94
                  .|.....|..|.:        ||.            |.:..|...:|..:.|.
Frog   165 SFHANIRKLTGGADKGKFVALENISCKIKSGCEGHPPWPEGICTKCQPSAITLNRQKYRHVDNIM 229

  Fly    95 ------ADPF----RLTGNARIMLYQQLKRDLRHGRLY--------CSLGEAAALGALIVQEELG 141
                  ||.|    |.|||.||            |.||        ..||..|.:.|:....::|
Frog   230 FENHTIADRFLDFWRKTGNQRI------------GYLYGRYTEHKDIPLGLRAEVAAIYEPPQIG 282

  Fly   142 DYNE----DVHVGSYVSSI--ELALRQTECLEKKIIELHKKREPGQNLSLAMDEFLGIARGLETY 200
            ..|.    |......|..|  :|.||:...:...::. ...|:.....|...|.:...|....|.
Frog   283 TQNSLQLLDDPKAKVVDEIAAKLGLRKVGWIFTDLVS-EDTRKGTVRYSRNKDTYFLSAEECITS 346

  Fly   201 GI--DPHP------VKDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEG 248
            |.  :.||      ...|.|| ::|.:..||      |..:|         ::|||
Frog   347 GFFQNKHPNLCRLSPDGHFGS-KFVTVVATG------GPDNQ---------VHFEG 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5022	NP_609384.1	B41	13..205	CDD:214604	50/254 (20%)
		FERM_N	16..80	CDD:286467	17/94 (18%)
		FERM_M	108..205	CDD:278785	21/112 (19%)
		FERM_C_FRMD3_FRMD5	186..294	CDD:270013	17/71 (24%)
		FA	308..349	CDD:285894
nploc4	NP_001135712.1	UN_NPL4	1..80	CDD:338032
		zf-NPL4	107..247	CDD:368244	29/146 (20%)
		NPL4	250..558	CDD:368245	36/166 (22%)
		RanBP2-type Zn finger	586..605	CDD:275376
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900