DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5022 and epb41l1

DIOPT Version :9

Sequence 1:	NP_609384.1	Gene:	CG5022 / 34398	FlyBaseID:	FBgn0032225	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_012808193.1	Gene:	epb41l1 / 100127644	XenbaseID:	XB-GENE-877327	Length:	1292	Species:	Xenopus tropicalis

Alignment Length:	397	Identity:	138/397 - (34%)
Similarity:	203/397 - (51%)	Gaps:	16/397 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 CTVRLLDDSDVLECEFQPFHKGIYLLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSKSIIKQC 78
            |.|.|||.|: .|||.:...:|..|.:.:||.|.:.|||||||.:.|:..|::|||.||.|.||.
Frog    88 CRVTLLDSSN-YECEIEKHARGQVLFDTVCGHLNLLEKDYFGLTFCDTDSQKNWLDPSKEIKKQI 151

  Fly    79 K-EMDPLLFSLRVKFYPADPFRLTGN-ARIMLYQQLKRDLRHGRLYCSLGEAAALGALIVQEELG 141
            | |.....|...|||||.||.:||.: .|..|..||:.|:..|||.||....|.||:..||.|||
Frog   152 KSECGAWTFGFTVKFYPPDPSQLTEDITRYYLCLQLRADIISGRLPCSFVTHALLGSYTVQAELG 216

  Fly   142 DYNEDVHVGSYVSSIELALRQTECLEKKIIELHKKREPGQNLSLAMDEFLGIARGLETYGIDPHP 206
            ||:.:.:.|:|||.:..:..||..||::|:||||... |...:.|...||..|:.|..||:|.|.
Frog   217 DYDPEENHGNYVSELRFSPNQTRELEERIMELHKTYR-GMTPAEAEIHFLENAKKLSMYGVDLHH 280

  Fly   207 VKDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEGKMFIAHLSYTDASREPKKHTVGF 271
            .||..|....:|:...|:..:....|...|.|.:|.||:::...|  ::.......|..:.|:||
Frog   281 AKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNF--YIKIRPGEYEQFESTIGF 343

  Fly   272 KCPTGAACRYLWRCAIEQMLFFTLPNSQSAAVISGGGFFSWGTKFRYTGRTEREILTENINALRE 336
            |.|...|.:.||:..||...||.|.:.:.|.    .||...|:||||:|||:.:  |:..:||.:
Frog   344 KLPNHRAAKRLWKVCIEHHTFFRLVSPEPAP----KGFLVMGSKFRYSGRTQAQ--TQQASALID 402

  Fly   337 QKNNSNSSKRKASSVPATPSSPQGDLAQIRYSSLPRSTMSEPLGYGMPNGHFYGHDHGMSDANGG 401
            :.  :.:.||.:|.......|.:|..:  |.:::..:..|.|......:|.....:.|..:....
Frog   403 RP--APNFKRSSSKRYTLSQSQEGGFS--RPTAVNENHESSPEKNHEDHGEELDREEGQEEVTTP 463

  Fly   402 IQISSLE 408
            .:|..|:
Frog   464 TKIKELK 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5022	NP_609384.1	B41	13..205	CDD:214604	85/192 (44%)
		FERM_N	16..80	CDD:286467	31/64 (48%)
		FERM_M	108..205	CDD:278785	41/96 (43%)
		FERM_C_FRMD3_FRMD5	186..294	CDD:270013	33/107 (31%)
		FA	308..349	CDD:285894	15/40 (38%)
epb41l1	XP_012808193.1	B41	88..279	CDD:214604	85/192 (44%)
		FERM_N	90..153	CDD:286467	30/63 (48%)
		FERM_M	172..279	CDD:278785	44/107 (41%)
		FERM_C_4_1_family	274..367	CDD:270005	29/94 (31%)
		FA	376..416	CDD:285894	16/43 (37%)
		SAB	481..522	CDD:282265
		4_1_CTD	<1224..1279	CDD:283537
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	73	1.000	Domainoid score	I9050
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000