Protein Alignment Sps2 and Sephs1

DIOPT Version :10

• Sequence 1: NP_477478.4
• Gene: Sps2 / 34397
• FlyBaseID: FBgn0032224
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001098100.1
• Gene: Sephs1 / 291314
• RGDID: 1311182
• Length: 392
• Species: Rattus norvegicus
• Alignment Length: 376
• Identity: 160/376 - (42%)
• Similarity: 234/376 - (62%)
• Gaps: 14/376 - (3%)

  Fly     2 FQPEKHGLEPDFQLTKFTTHTGUSCKIPQKVLEKYLRGTEIENKNNDGYLIGS-------GMDCA 59
            |.||.:.|:..|:||:||...|..||:||.||:|.|...:..:...|...:|:       |||..
  Rat     7 FNPETYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDEQFLGAVMPRLGIGMDTC 71

  Fly    60 VIPLKRHKDYLLIQTVDFFYPMVNDPELLGRIALANVLSDVYAVGVTQFDTVEMIVSTSTSFSEK 124
            |||| ||....|:||.|:.||:|:||.::||||.||||||:||:|||:.|.:.|::..|...:::
  Rat    72 VIPL-RHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDR 135

  Fly   125 ERDVVIGLVMKGFQNSLKANGYRNTPLIIRQLKINPWCIIGGIATSVCRSEEIILPSNAQPGDVL 189
            |||.|:.|:::||:::.:..|   |.:...|..:|||.::||:||:||:..|.|:|.||.|||||
  Rat   136 ERDKVMPLIIQGFKDAAEEAG---TSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVL 197

  Fly   190 VLTKPLGGQMAMDAHLWQLNQTEKYKKLLSECSDADIKETFEIAVKSMTYLNKNAALLMHKYQAH 254
            |||||||.|:|:..|.| |:..||:.|:....:..|::..::.|:.:|..||:.||.|||.:.||
  Rat   198 VLTKPLGTQVAVAVHQW-LDIPEKWNKIKLVVTQEDVELAYQEAMVNMARLNRTAAGLMHTFNAH 261

  Fly   255 CATDITGFGLLGHANNLAQFQKEKVLFQINKLPIIKNVLKFSTLVGQSTKFRSGRSVETSGGLLI 319
            .||||||||:||||.|||:.|:.:|.|.|:.||::..:...|...|.......|...||||||||
  Rat   262 AATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLI 326

  Fly   320 CLPADAADKFCRDFEEATNGE-QKSFQIGHVTAANESDAVLCEDVEFIEVS 369
            |||.:.|.:||.:.:....|| .:::.||.|...|.: |.:.:....|||:
  Rat   327 CLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRT-ARIIDKPRIIEVA 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sps2	NP_477478.4	SelD	15..349	CDD:100031	149/341 (44%)
Sephs1	NP_001098100.1	selD	19..333	CDD:273100	142/318 (45%)