Protein Alignment Sps2 and SEPHS2

DIOPT Version :10

• Sequence 1: NP_477478.4
• Gene: Sps2 / 34397
• FlyBaseID: FBgn0032224
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_036380.2
• Gene: SEPHS2 / 22928
• HGNCID: 19686
• Length: 448
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 166/395 - (42%)
• Similarity: 237/395 - (60%)
• Gaps: 35/395 - (8%)

  Fly     2 FQPEKHGLEPDFQLTKFTTHTGUSCKIPQKVLEKYLRGT----------------EIENKNNDGY 50
            |:|:..||.|.::||.|:...| .||:||:.|.|.|.|.                :.|.....|.
Human    38 FEPQALGLSPSWRLTGFSGMKGUGCKVPQEALLKLLAGLTRPDVRPPLGRGLVGGQEEASQEAGL 102

  Fly    51 -----------LIGSGMDCAVIPLKRHKDYLLIQTVDFFYPMVNDPELLGRIALANVLSDVYAVG 104
                       .:|.|||..|||| ||....|:||.|||||:|.||.::||||.||||||:||:|
Human   103 PAGAGPSPTFPALGIGMDSCVIPL-RHGGLSLVQTTDFFYPLVEDPYMMGRIACANVLSDLYAMG 166

  Fly   105 VTQFDTVEMIVSTSTSFSEKERDVVIGLVMKGFQNSLKANGYRNTPLIIRQLKINPWCIIGGIAT 169
            :|:.|.:.|::|.|.|.||:||:.|..|::|||:::.:..|   |.:...|..:|||.||||:||
Human   167 ITECDNMLMLLSVSQSMSEEEREKVTPLMVKGFRDAAEEGG---TAVTGGQTVVNPWIIIGGVAT 228

  Fly   170 SVCRSEEIILPSNAQPGDVLVLTKPLGGQMAMDAHLWQLNQTEKYKKLLSECSDADIKETFEIAV 234
            .||:..|.|:|.:|..|||||||||||.|:|::||.| |:..|::.|:....|..:::..::.|:
Human   229 VVCQPNEFIMPDSAVVGDVLVLTKPLGTQVAVNAHQW-LDNPERWNKVKMVVSREEVELAYQEAM 292

  Fly   235 KSMTYLNKNAALLMHKYQAHCATDITGFGLLGHANNLAQFQKEKVLFQINKLPIIKNVLKFSTLV 299
            .:|..||:.||.|||.:.||.||||||||:|||:.|||:.|:.:|.|.|:.||||..:...|...
Human   293 FNMATLNRTAAGLMHTFNAHAATDITGFGILGHSQNLAKQQRNEVSFVIHNLPIIAKMAAVSKAS 357

  Fly   300 GQSTKFRSGRSVETSGGLLICLPADAADKFCRDFEEATNGE-QKSFQIGHVTAANESDAVLCEDV 363
            |:....: |.|.|||||||||||.:.|.:||.:.:.:..|| .:::.:|.|...|.: |.:.:..
Human   358 GRFGLLQ-GTSAETSGGLLICLPREQAARFCSEIKSSKYGEGHQAWIVGIVEKGNRT-ARIIDKP 420

  Fly   364 EFIEV 368
            ..|||
Human   421 RVIEV 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sps2	NP_477478.4	SelD	15..349	CDD:100031	156/361 (43%)
SEPHS2	NP_036380.2	SelD	51..407	CDD:100031	156/361 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	85..107		2/21 (10%)