Protein Alignment SamDC and AMD1

DIOPT Version :10

• Sequence 1: NP_477223.2
• Gene: SamDC / 34396
• FlyBaseID: FBgn0019932
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001625.2
• Gene: AMD1 / 262
• HGNCID: 457
• Length: 334
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 167/345 - (48%)
• Similarity: 221/345 - (64%)
• Gaps: 26/345 - (7%)

  Fly     6 SHFFEGVEKLLEIWFE----ESSNGDDDLRNISRSDWENVLSNVNCQIISTSKNDIIDAFVLSES 66
            :|||||.|||||:||.    :::.|..|||.|.||:|:.:|.:|.|.|||.:|.|..:|:|||||
Human     4 AHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSES 68

  Fly    67 SMFVSKRRWILKTCGTTTPLKCLGQLLKLA-EANGYNVVADLFYSRKNFTRPEAQITPHQGFTEE 130
            ||||||||:||||||||..||.|..||||| :.:|::.:...|||||||.:|..|..||:.|.||
Human    69 SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEE 133

  Fly   131 VTYLDSIFPNGRSYCLGSMNLECWYLYTFSRSDIKITPQLISDEKNVDSDPDQTIEILMQDLDPE 195
            :.:|::|||||.:||:|.||.:||||||           |...|..|.|.||||:||||.:|||.
Human   134 IEFLNAIFPNGAAYCMGRMNSDCWYLYT-----------LDFPESRVISQPDQTLEILMSELDPA 187

  Fly   196 TMSIFYKNKFNDANGATVKSGIDTILPTMHIDDFLFDPCGYSMNGINDKGEYMTIHITPENQFSY 260
            .|..||......|...|.:|||..::|...||..:|:||||||||:...|.|.|||||||.:|||
Human   188 VMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSY 252

  Fly   261 VSFETNVALSNYRKLINQVINTFKPGKFIVTIFAN---KCSLAYETMKELEVEYSQGSHWKRTDM 322
            ||||||::.::|..||.:|:..||||||:.|:|.|   ||.....:.:::|       .:||.|.
Human   253 VSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIE-------GFKRLDC 310

  Fly   323 QCCNFPSYNLLFAQYSHSEK 342
            |...|..||.:|..::..::
Human   311 QSAMFNDYNFVFTSFAKKQQ 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SamDC	NP_477223.2	SAM_decarbox	6..337	CDD:460243	167/338 (49%)
AMD1	NP_001625.2	SAM_decarbox	4..325	CDD:460243	167/338 (49%)