DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAd and Gata3

DIOPT Version :9

Sequence 1:	NP_001260326.1	Gene:	GATAd / 34395	FlyBaseID:	FBgn0032223	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_579827.1	Gene:	Gata3 / 85471	RGDID:	621250	Length:	444	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	100/389 - (25%)
Similarity:	145/389 - (37%)	Gaps:	115/389 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   454 QNEIQDGVEIDLSVKKQKND----YSNQRNAA-----PIHH---FCQTPMLD------------I 494
            |..:.:.|::..::..|.|.    |.|...|.     |.||   .|:.|:|.            .
  Rat    40 QYPLTEEVDVLFNIDGQGNHVPSYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALS 104

  Fly   495 QSHLRSEEDFQNYSITINQVGGSDFKSKAPKASTGSLLDSGDSSDSHKLEMDIT----------- 548
            ..|..|..:...:|.|....|.....|..|.||:.||. :|.|| .|......|
  Rat   105 SHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLA-AGHSS-PHLFTFPPTPPKDVSPDPSL 167

  Fly   549 -------SSINDRK--------TPDS--LSSDHATDAATTQLWQALARSAAKSKEDNPASQIFRN 596
                   |:..|.|        .|||  |.:.|:..:.||       ...|.|...:|.:
  Rat   168 STPGSAGSARQDEKECLKYQVQLPDSMKLETSHSRGSMTT-------LGGASSSAHHPIT----- 220

  Fly   597 MMSQPFAFPVPSTVSFTKVPEEPIALLKDLSEAQSSKSKPCRRKQSFPTKTDCIDVVNENVTDTY 661
                  .:| |....::.....|.:||.........||:|..|     :.|:..:.||...|
  Rat   221 ------TYP-PYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKAR-----SSTEGRECVNCGAT--- 270

  Fly   662 TTSEATPDDKKDKRNINLFNA------IPGAQKDM---------------SCSNCGTLTTTIWRR 705
                :||..::|.....|.||      :.|..:.:               ||:||.|.|||:|||
  Rat   271 ----STPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRR 331

  Fly   706 SVRGEMVCNACGLYFKLHGVNRPHSMRRDTIHTRRRRPKELERSKKKHKQMSSCSSIETTKQDF 769
            :..|:.||||||||:|||.:|||.:|:::.|.||.|  |...:|||       |..:....:||
  Rat   332 NANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNR--KMSSKSKK-------CKKVHDALEDF 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_001260326.1	zf-AD	<228..284	CDD:214871
		ZnF_GATA	688..736	CDD:214648	27/62 (44%)
		ZnF_GATA	691..742	CDD:238123	30/50 (60%)
Gata3	NP_579827.1	ZnF_GATA	263..313	CDD:238123	10/56 (18%)
Gata3	NP_579827.1	ZnF_GATA	317..367	CDD:238123	30/49 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334671
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740