DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAd and DAL80

DIOPT Version :9

Sequence 1:	NP_001260326.1	Gene:	GATAd / 34395	FlyBaseID:	FBgn0032223	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_012959.1	Gene:	DAL80 / 853904	SGDID:	S000001742	Length:	269	Species:	Saccharomyces cerevisiae

Alignment Length:	174	Identity:	49/174 - (28%)
Similarity:	82/174 - (47%)	Gaps:	37/174 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   691 SCSNCGTLTTTIWRRSVRGEMVCNACGLYFKLHGVNRPHSMRRDTIHTRRRRPKELERS------ 749
            :|.||.|:.|.:|||...|.::||||||:.||||..||.|::.|||.:|.|  |:|..:
Yeast    30 TCQNCFTVKTPLWRRDEHGTVLCNACGLFLKLHGEPRPISLKTDTIKSRNR--KKLNNNNVNTNA 92

  Fly   750 -----------KKKHKQMSSCSSIETTKQDFLTARESLAISGLV--LNKFKKEIDDTETPAAAAL 801
                       |:|.:.:::......|....::..|...:||.:  |.|.|:.:.:|
Yeast    93 NTHSNDPNKIFKRKKRLLTTGGGSLPTNNPKVSILEKFMVSGSIKPLLKPKETVPNT-------- 149

  Fly   802 KDILSRRKKSNSLPAFNDTCESADLSAPLNLVSSE---NNAKLT 842
            |:..::|.|.:.     |.||.:..:....:..|:   :|.:||
Yeast   150 KECSTQRGKFSL-----DPCEPSGKNYLYQINGSDIYTSNIELT 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_001260326.1	zf-AD	<228..284	CDD:214871
		ZnF_GATA	688..736	CDD:214648	23/44 (52%)
		ZnF_GATA	691..742	CDD:238123	26/50 (52%)
DAL80	NP_012959.1	GAT1	<1..269	CDD:227928	49/174 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341364
Domainoid	1	1.000	54	1.000	Domainoid score	I2764
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16864
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.770