Protein Alignment GATAd and TRPS1

DIOPT Version :10

• Sequence 1: NP_609383.2
• Gene: GATAd / 34395
• FlyBaseID: FBgn0032223
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_054831.2
• Gene: TRPS1 / 7227
• HGNCID: 12340
• Length: 1294
• Species: Homo sapiens
• Alignment Length: 791
• Identity: 163/791 - (20%)
• Similarity: 274/791 - (34%)
• Gaps: 217/791 - (27%)

  Fly   104 SQQIQSQTLHHHQNQTKIHYTPSVPSAADAKSSERERQCQLESDIAERSTVFKSQSSSD----HE 164
            |.:::...|..|.|:.|    .|:||:..||.||:.....:.:        .:|..|.|    .:
Human   360 STELEQHFLQTHPNKIK----ASLPSSEVAKPSEKNSNKSIPA--------LQSSDSGDLGKWQD 412

  Fly   165 HIEYSGETPSPSASLSQSQTKSEPMREEEEHQHNHNQQSGREETSV-----------NTTNISGT 218
            .|.......:|..       .|.|::..:.     ::|:|.|.||.           :::::...
Human   413 KITVKAGDDTPVG-------YSVPIKPLDS-----SRQNGTEATSYYWCKFCSFSCESSSSLKLL 465

  Fly   219 DNYGKEHGRDDSS--SPHLTFQIFNCLSIKALPNDGLPNVVCGDCRQKLD--------------S 267
            ::|||:||...|.  :|.|..::.....|.  .|| |.....|:...|.|              .
Human   466 EHYGKQHGAVQSGGLNPELNDKLSRGSVIN--QND-LAKSSEGETMTKTDKSSSGAKKKDFSSKG 527

  Fly   268 FEKFRTMAHNSQIALKEFLNISKNLRPD----------------------------PNDL---ET 301
            .|.....::|.|..  :| ..||:..||                            |..|   |.
Human   528 AEDNMVTSYNCQFC--DF-RYSKSHGPDVIVVGPLLRHYQQLHNIHKCTIKHCPFCPRGLCSPEK 589

  Fly   302 KLDAI-----LKASSEAIAAKALTELST----FSKVKYDHSKLDSSIQPGLDRKIEISNQEMPAH 357
            .|..|     .:.|:.:..|..|..||.    .|:||:...:. |...|.:|        .:..|
Human   590 HLGEITYPFACRKSNCSHCALLLLHLSPGAAGSSRVKHQCHQC-SFTTPDVD--------VLLFH 645

  Fly   358 SLYPSLFKSITMKSDQKSKAMSGSSHSQFDSKLQKDSDIEKYENLQQQLETAAVLMDISKKIVIS 422
              |.|:.:|......|::..:.||...| ..|..|:....|.:.:.|..|      :||:....:
Human   646 --YESVHESQASDVKQEANHLQGSDGQQ-SVKESKEHSCTKCDFITQVEE------EISRHYRRA 701

  Fly   423 PPCSNPQSPCFSAAVDTSIKSSVIKSKRPSNQNEIQDGVEIDLSVKKQKNDYSNQRNAAPIHHFC 487
            ..|...:...|:|| ||                  |..:|...:|..|:.|.:........|..
Human   702 HSCYKCRQCSFTAA-DT------------------QSLLEHFNTVHCQEQDITTANGEEDGHAI- 746

  Fly   488 QTPMLDIQSHLRSEE--DFQNYSITINQVGGSDFKSKAPKASTGSLLDSGDSSDSHKLEMDITSS 550
                    |.::.|.  ||:.|::..     .|.|...|.:.:....:..:..|..|.::...||
Human   747 --------STIKEEPKIDFRVYNLLT-----PDSKMGEPVSESVVKREKLEEKDGLKEKVWTESS 798

  Fly   551 INDRKT-----PDSLSSDHATDAATTQLWQALA--RSAAKSKEDNPASQIFRNMMSQPFAFPVPS 608
            .:|.:.     .|.|....:...|:..|...::  :...|:..|:|      |:.:...|.|:..
Human   799 SDDLRNVTWRGADILRGSPSYTQASLGLLTPVSGTQEQTKTLRDSP------NVEAAHLARPIYG 857

  Fly   609 TVSFTKVPEEPIALLKDLSEAQSSKSKPCRRKQSFPTKTDCIDVVNENVTDTYTTSEATPDDKKD 673
            ....||         ..|..|.:...|.....|.:|                     |:.::|..
Human   858 LAVETK---------GFLQGAPAGGEKSGALPQQYP---------------------ASGENKSK 892

  Fly   674 KRNINLFNAIPGAQKDMSCSNCGTLTTTIWRRSVRGEMVCNACGLYFKLHGVNRP---------- 728
            ..:.:|.....|:  .:.|:||.|..|::||::..|..||||||||.|||...||
Human   893 DESQSLLRRRRGS--GVFCANCLTTKTSLWRKNANGGYVCNACGLYQKLHSTPRPLNIIKQNNGE 955

  Fly   729 HSMRRDTIHTRRRRPKELERSKKKHKQMSS------CSSIETTKQDFLTARESLAISGLVLNKFK 787
            ..:||.|  .:|..|:.|:..:...:|..|      .|.:|...:|.||......|....|:|::
Human   956 QIIRRRT--RKRLNPEALQAEQLNKQQRGSNEEQVNGSPLERRSEDHLTESHQREIPLPSLSKYE 1018

  Fly   788 KEIDDTETPAA 798
            .:...|::.:|
Human  1019 AQGSLTKSHSA 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_609383.2	zf-AD	<228..284	CDD:214871	13/71 (18%)
		GAT1	625..>742	CDD:227928	34/126 (27%)
		ZnF_GATA	691..742	CDD:238123	25/60 (42%)
TRPS1	NP_054831.2	ZnF_GATA	908..964	CDD:238123	24/57 (42%)