DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAd and gata1a

DIOPT Version :9

Sequence 1:	NP_001260326.1	Gene:	GATAd / 34395	FlyBaseID:	FBgn0032223	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_571309.2	Gene:	gata1a / 30481	ZFINID:	ZDB-GENE-980526-268	Length:	418	Species:	Danio rerio

Alignment Length:	384	Identity:	107/384 - (27%)
Similarity:	147/384 - (38%)	Gaps:	108/384 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   420 VISPPCSNPQSPCFSAAVDTSIKSSVIKSKRPSNQNEIQDGVEI-----------DLSVKKQKND 473
            |..|..|:.::....:...||::|....|.|.|...::.....|           ..|:....|.
Zfish    36 VDEPFYSSSETDLLPSYYSTSVQSRASSSYRHSPVRQVYSSQSILGNIQWLDNSAGHSLNSPYNP 100

  Fly   474 YSNQRNAAPIHHFCQTPMLDIQSHLRSEEDFQNYSITINQVGGSDFKSKAPKASTGSLLDSGDSS 538
            .|...:::|   |.:||   :.|| .|...:||       .....|.|  ||....|  .|.|..
Zfish   101 TSTVWSSSP---FAKTP---LHSH-TSTSIYQN-------TATPSFTS--PKEGFPS--PSRDGK 147

  Fly   539 DSHKLEMDITSSINDRKTPDSLSSDHATDAATTQLWQALARSAAKSKEDNPASQIFRNMMSQPFA 603
            ||.:|:..:.:   :|.:|.|.|..           ..|..|:|......|:.    :|:|
Zfish   148 DSPRLQEVLKA---ERLSPMSGSGS-----------SFLNLSSATGGVYGPSP----HMLS---- 190

  Fly   604 FPVPSTVSFTKVPEEPIALLKDLSEA-----------QSSKSKPCRRKQ--SFPTKTDCIDVVNE 655
             |..|.:|.:          :|.|.|           .||.|...|.|.  |.|...:|   ||.
Zfish   191 -PYGSYMSTS----------QDYSSAALYSTGGPWMSPSSYSPKLRNKMRLSPPEAREC---VNC 241

  Fly   656 NVTDTYTTSEATPDDKKDKRNINLFNA---------------------IPGAQKDMSCSNCGTLT 699
            ..|       |||..::|.....|.||                     |...:....|:||.|.|
Zfish   242 GAT-------ATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCANCHTST 299

  Fly   700 TTIWRRSVRGEMVCNACGLYFKLHGVNRPHSMRRDTIHTRRRRPKELERSKKKHKQMSS 758
            ||:|||:..||.||||||||||||.||||.:|::|.|.||.|  |...|:||..|..:|
Zfish   300 TTLWRRNASGEPVCNACGLYFKLHNVNRPLTMKKDGIQTRNR--KVSNRNKKGKKNAAS 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_001260326.1	zf-AD	<228..284	CDD:214871
		ZnF_GATA	688..736	CDD:214648	30/47 (64%)
		ZnF_GATA	691..742	CDD:238123	33/50 (66%)
gata1a	NP_571309.2	ZnF_GATA	237..281	CDD:238123	11/53 (21%)
gata1a	NP_571309.2	ZnF_GATA	291..342	CDD:238123	34/52 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573876
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840