DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAd and SPCC1393.08

DIOPT Version :9

Sequence 1:	NP_001260326.1	Gene:	GATAd / 34395	FlyBaseID:	FBgn0032223	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_587966.1	Gene:	SPCC1393.08 / 2538884	PomBaseID:	SPCC1393.08	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	553	Identity:	119/553 - (21%)
Similarity:	204/553 - (36%)	Gaps:	172/553 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 YPSLFKSITMKSDQKSKAMSGSSHSQFDS----KLQKDSDIEKYENLQQQLETAAVL----MDI- 415
            ||..|.|  .:::||.:....:..|..||    ..::.||:|..:.....|..:.:|    :||
pombe    86 YPLAFNS--TENNQKLQTNPSARWSLLDSMDFDNQRQCSDLESAQLGDSGLLKSTILSNSHIDIA 148

  Fly   416 ----SKKIVISPPCSNPQSPCF----SAAVDTSIKSSVIKSKRPSNQNEIQDGVEIDLSVKKQKN 472
                ||....:||.|..|:||.    ||.:||....::                         .:
pombe   149 ALSSSKTSEPTPPFSYVQTPCIPTPSSALIDTPFPGAL-------------------------DS 188

  Fly   473 DYSNQRNAAPIHHF----CQTPMLDIQSHLRSEEDFQNYSITINQVGGSDFKSKAPKASTGSLLD 533
            ::....:.||:...    ||.....|...       .||...::.:|   |.|.
pombe   189 EFGFDESQAPLFPASDGDCQRAFASISYP-------TNYGCKLSNLG---FMSP----------- 232

  Fly   534 SGDSSDSHKLEMDITSSINDRKTPDSL--SSDHATDAATTQLWQALARSAAKSKEDNPAS----- 591
                      :..:...:||..:|..|  ||...|.:::..|.|:....:..|..|:.|:
pombe   233 ----------QSPVKRELNDSTSPSKLSESSSSLTGSSSALLSQSEFLGSVPSLSDSIATVDPFF 287

  Fly   592 --QIFR----------------------NMMSQPFAFPVPSTVSFTKVPEEPIALLKDLSEAQSS 632
              :.|.                      |:.|...:..:.||::.......|:|.:|  :|..|.
pombe   288 SFESFETDEKARSLLMDASLKLPQFSTPNLSSNSSSLSLKSTLAEGMKGSTPLAAVK--TEKASK 350

  Fly   633 KSKPCRRKQSFPTKTDCIDVVNENVTDTYTTSEATPDDKKDKRNI-----NLFNAIPGAQKDMS- 691
            .::..::|:.  .:..|.   |..||:|......:     ||.|.     .|:|...|..:.:|
pombe   351 AARVMKQKKH--REHVCF---NCGVTETPLWRRTS-----DKLNFLCNACGLYNKQYGVMRPLSP 405

  Fly   692 -------------CSNCGTLTTTIWRRSVRGEMVCNACGLYFKLHGVNRPHSMRRDTIHTRRRRP 743
                         |:||.:..|::||:...|:.||||||||.:|||.|||..::::.| |||||.
pombe   406 RNKGSSKALENLVCANCSSTKTSLWRKDRHGQTVCNACGLYARLHGHNRPIGLKKNKI-TRRRRG 469

  Fly   744 KELERSKKKHKQMSSCSSIETTKQDFLTARESLAISGLVLNKFKKEIDDTETPAAAALKDILSRR 808
            |    .......||     :..|.:|....:|:.::.::.:|      ..|:|   .|.:.:|..
pombe   470 K----GPGGEDGMS-----DEVKSEFPVLSKSVTMAEILSSK------GLESP---QLTNSVSVS 516

  Fly   809 KKSNSLPAFNDTCESADLS---APLNLVSSENN 838
            |..|:         .||:|   |.::..|.:|:
pombe   517 KMPNT---------DADVSLEHAKISFDSLDNS 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_001260326.1	zf-AD	<228..284	CDD:214871
		ZnF_GATA	688..736	CDD:214648	22/61 (36%)
		ZnF_GATA	691..742	CDD:238123	26/64 (41%)
SPCC1393.08	NP_587966.1	GAT1	31..557	CDD:227928	119/553 (22%)
		ZnF_GATA	364..413	CDD:238123	12/56 (21%)
		ZnF_GATA	418..462	CDD:238123	21/43 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910