DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAd and elt-1

DIOPT Version :9

Sequence 1:	NP_001260326.1	Gene:	GATAd / 34395	FlyBaseID:	FBgn0032223	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_001033435.1	Gene:	elt-1 / 177794	WormBaseID:	WBGene00001249	Length:	488	Species:	Caenorhabditis elegans

Alignment Length:	415	Identity:	100/415 - (24%)
Similarity:	147/415 - (35%)	Gaps:	123/415 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   455 NEIQDGVEIDLSVKKQKNDY--------------------SNQRNAAPIHHFCQTPMLDIQSHLR 499
            |.|.|.:.|...::::..||                    ::...||.|..|         |:..
Worm    56 NSIIDALHISQPIEQENMDYEGKPVEFTLGTSSGGASLAPTSSTTAASIAPF---------SYNT 111

  Fly   500 SEEDFQN-----YSITIN-QVGGSDFKSKAPKASTGSLLDSGDSSDSHKLEMDITSSINDRKTPD 558
            |..::.|     |.:.:| |..|....:....|.:|               ||::.:.....|.:
Worm   112 SATNYYNTTPSSYPMFLNYQYAGGTTVTTDMDAFSG---------------MDMSMNNGVFGTQN 161

  Fly   559 SLSSDHATDAATTQLWQALARSAAKSKEDNPASQIFRNMMS-------QPFAFPVPSTVSFTK-- 614
            :.|..:.|....|..:..||.:...|......:|:..|::.       ||....:.||||..:
Worm   162 NPSYFYPTTQLNTYGYDTLAAATTASGITVNNNQLNVNIVQGNGTIVPQPITQNIISTVSNVQSS 226

  Fly   615 ------VPEEPIALLK-DLSEAQSSKSKPCRRKQSFPTKT---------------------DCID 651
                  .|..|..|.. ..|...||.|.......|.|..|                     :|::
Worm   227 VPINNSQPLTPTGLAGCSTSSGSSSASSSSANSTSTPKNTISKANRSSGGANNSQFSTEDRECVN 291

  Fly   652 VVNENV-------TDTYTTS----------EATPDDKKDKRNINLFNAIPGAQK--DMSCSNCGT 697
            ....|.       :..|..:          .|.|..|..||..|       |||  .:.|.||.|
Worm   292 CGVHNTPLWRRDGSGNYLCNACGLYFKMNHHARPLVKPKKRQQN-------AQKRTGIECVNCRT 349

  Fly   698 LTTTIWRRSVRGEMVCNACGLYFKLHGVNRPHSMRRDTIHTRRRR--PKELERSKKKHKQMSSCS 760
            .|||:|||:..|..||||||||||||.|.||.:|::|.|.||.|:  .|...|.||::....:..
Worm   350 NTTTLWRRNGEGHPVCNACGLYFKLHKVERPITMKKDGIQTRNRKLSAKGSRRMKKENGGTPTSM 414

  Fly   761 SIETTKQDFLTARESLAISGLVLNK 785
            .:.||        .|...||:.|::
Worm   415 GMPTT--------SSSISSGIELDQ 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_001260326.1	zf-AD	<228..284	CDD:214871
		ZnF_GATA	688..736	CDD:214648	29/49 (59%)
		ZnF_GATA	691..742	CDD:238123	31/50 (62%)
elt-1	NP_001033435.1	ZnF_GATA	285..332	CDD:214648	6/46 (13%)
		ZnF_GATA	288..339	CDD:238123	11/57 (19%)
		ZnF_GATA	339..388	CDD:214648	28/48 (58%)
		ZnF_GATA	343..394	CDD:238123	31/50 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2600
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860