Protein Alignment GATAd and GATA5

DIOPT Version :10

• Sequence 1: NP_609383.2
• Gene: GATAd / 34395
• FlyBaseID: FBgn0032223
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_536721.1
• Gene: GATA5 / 140628
• HGNCID: 15802
• Length: 397
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 70/270 - (25%)
• Similarity: 115/270 - (42%)
• Gaps: 82/270 - (30%)

  Fly   595 RNMMSQPFAFPVPSTVSFTKVPEEPIALLKDLSEAQSS--------KSKPCRRK-------QSFP 644
            |...:.|...||.::.|.|    .|..:..|::::.::        ...|.||.       :.||
Human   123 REQFAAPLGRPVGTSYSAT----YPAYVSPDVAQSWTAGPFDGSVLHGLPGRRPTFVSDFLEEFP 183

  Fly   645 TK-TDCIDVVNENVTDTYTTSEATPDDKKDKRNINLFNA-------------IPGAQKDMS---- 691
            .: .:|::          ..:.:||..::|.....|.||             :...||.:|
Human   184 GEGRECVN----------CGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRR 238

  Fly   692 ----CSNCGTLTTTIWRRSVRGEMVCNACGLYFKLHGVNRPHSMRRDTIHTRRRRPKELERSK-- 750
                |:||.|..||:|||:..||.||||||||.|||||.||.:|::::|.||:|:||.:.:::
Human   239 AGLCCTNCHTTNTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGS 303

  Fly   751 --KKHKQMSSCSSIETTKQDFLTAR------------------------ESLAISGLVLNKFKKE 789
              ......:|.|::.:|.....|::                        :|||...|   :||.|
Human   304 SGSTRNASASPSAVASTDSSAATSKAKPSLASPVCPGPSMAPQASGQEDDSLAPGHL---EFKFE 365

  Fly   790 IDDTETPAAA 799
            .:|...|:.|
Human   366 PEDFAFPSTA 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_609383.2	zf-AD	<228..284	CDD:214871
		GAT1	625..>742	CDD:227928	46/153 (30%)
		ZnF_GATA	691..742	CDD:238123	31/58 (53%)
GATA5	NP_536721.1	GATA-N	1..170	CDD:461628	9/50 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..116
		ZnF_GATA	188..232	CDD:238123	8/53 (15%)
		ZnF_GATA	<253..293	CDD:238123	24/39 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..356		12/74 (16%)