DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAd and ZGLP1

DIOPT Version :9

Sequence 1:	NP_001260326.1	Gene:	GATAd / 34395	FlyBaseID:	FBgn0032223	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_001096637.1	Gene:	ZGLP1 / 100125288	HGNCID:	37245	Length:	271	Species:	Homo sapiens

Alignment Length:	161	Identity:	41/161 - (25%)
Similarity:	60/161 - (37%)	Gaps:	59/161 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   618 EPIAL-----------LKDLSEAQSSKSK-----------PCR--RKQSFPTK-TDCIDVVNENV 657
            :|:||           .||.....|.|.:           |.|  |||..|.: |:.:|...|.|
Human    83 DPMALGTQGRLLLDRDSKDTQTRISQKGRRLQPPGTPSAPPQRRPRKQLNPCRGTERVDPGFEGV 147

  Fly   658 T--------------DTY-----TTSEATPDDKKDKRNINLFNAIPG----------AQKDMSCS 693
            |              .||     :.|:.:|.|.     :....|.||          |.:...|:
Human   148 TLKFQIKPDSSLQIIPTYSLPCSSRSQESPADA-----VGGPAAHPGGTEAHSAGSEALEPRRCA 207

  Fly   694 NCGTLTTTIWRRSVRGEMVCNACGLYFKLHG 724
            :|.|..|.:||.:..|..:|||||:.:|.:|
Human   208 SCRTQRTPLWRDAEDGTPLCNACGIRYKKYG 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_001260326.1	zf-AD	<228..284	CDD:214871
		ZnF_GATA	688..736	CDD:214648	14/37 (38%)
		ZnF_GATA	691..742	CDD:238123	14/34 (41%)
ZGLP1	NP_001096637.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..40
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..141		11/44 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..199		6/33 (18%)
		ZnF_GATA	202..>240	CDD:214648	14/37 (38%)
		GATA	206..240	CDD:278735	14/33 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141000
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740