DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAd and Zglp1

DIOPT Version :9

Sequence 1:	NP_001260326.1	Gene:	GATAd / 34395	FlyBaseID:	FBgn0032223	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_001096638.1	Gene:	Zglp1 / 100009600	MGIID:	3696042	Length:	266	Species:	Mus musculus

Alignment Length:	328	Identity:	65/328 - (19%)
Similarity:	114/328 - (34%)	Gaps:	113/328 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   409 AAVLMDISKK-IVISPPCSNPQSPCFSAAVDTSIKSSVIKSKRPSNQNEIQDGVEIDLSVKKQKN 472
            ||...|:::: .:::|||           :||   .|:.||:.|:    ::.|....|:
Mouse     3 AAQAGDLTRRQELLAPPC-----------LDT---ESLRKSRPPA----LEPGALRCLT------ 43

  Fly   473 DYSNQRNAAPIHHFCQTPMLDIQSHLRSEEDFQNYSITINQVGGSDFKSKAPKASTGSLLDSGDS 537
              .|.|:..|.   ||..:......|:.:|         ..:.||...:.....|...|:..|.|
Mouse    44 --PNIRSLWPT---CQDSVSTALPFLQEKE---------KGLPGSPSPATQVLGSCWELMVIGMS 94

  Fly   538 SDSHKLEMDITSSINDRKTP-DSLSSDHATDAATTQLWQALARSAAKSKEDNPASQI------FR 595
            .       .::.:.|.|.|. .:|....||..|:.|        ....|:.||...|      |:
Mouse    95 D-------HLSMARNPRGTQCPNLEISSATSPASLQ--------RRPRKQLNPRMGIEKVDPRFK 144

  Fly   596 NMMSQPFAFPVPSTVSFTKVPEEPIALLKDLSEAQSSKSKPCRRK-QSFPTKTDCIDVVNENVTD 659
            .:           |:.|...|:..:.::    ...|...:.|.:| .:.|:|.
Mouse   145 GV-----------TLEFQIQPDSSLQIV----PTYSLPGRSCSQKLPASPSKA------------ 182

  Fly   660 TYTTSEATPDDKKDKRNINLFNAIPGAQKDMS---CSNCGTLTTTIWRRSVRGEMVCNACGLYFK 721
                                 .|.||:.:.:.   |::|.|..|.:||.:..|..:|||||:.:|
Mouse   183 ---------------------LASPGSSEALGPRRCASCRTQRTPLWRDAEDGTPLCNACGIRYK 226

  Fly   722 LHG 724
            .:|
Mouse   227 KYG 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAd	NP_001260326.1	zf-AD	<228..284	CDD:214871
		ZnF_GATA	688..736	CDD:214648	14/40 (35%)
		ZnF_GATA	691..742	CDD:238123	14/37 (38%)
Zglp1	NP_001096638.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31		11/41 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	106..129		6/30 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	171..191		7/52 (13%)
		ZnF_GATA	194..>231	CDD:214648	14/36 (39%)
		GATA	197..231	CDD:278735	14/33 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830955
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830