DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5037 and Cox10

DIOPT Version :9

Sequence 1:	NP_609382.1	Gene:	CG5037 / 34394	FlyBaseID:	FBgn0032222	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_848466.1	Gene:	Cox10 / 70383	MGIID:	1917633	Length:	443	Species:	Mus musculus

Alignment Length:	289	Identity:	167/289 - (57%)
Similarity:	217/289 - (75%)	Gaps:	5/289 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 KLSKFRLTSLVVITTMGGYAMAPAAFDPTTFAMCTLGTGLVSAAANAINQYHEVPFDSQMSRTKN 142
            :|||.:||:|||.||..|:|:||..||.:.|.:.:|||||.|.|||:|||:.||||||.|:||||
Mouse   158 RLSKIKLTALVVSTTSAGFALAPGPFDWSCFLLTSLGTGLASCAANSINQFFEVPFDSNMNRTKN 222

  Fly   143 RVLVTGQMTPLHAVTFAAVSATAGLSMLYFGVNGLTAALGAGNLFLYTTIYTPMKRISIVNTWVG 207
            |.||.||::||.||:||...|..|:::|.:|||.||.|||..|:||||..|||:||:||.|||||
Mouse   223 RPLVRGQISPLLAVSFATCCAVPGVALLTWGVNPLTGALGVFNIFLYTCCYTPLKRVSITNTWVG 287

  Fly   208 SIVGAIPPLMGWAGCAATLDAGAMILAGVLYAWQFPHFNALSWNLRPDYSRAGYRMMAVTNPGLC 272
            ::||||||:|||.....:|||||::|.|:||:|||||||||||.||.||||.||.||:||:|.||
Mouse   288 AVVGAIPPVMGWTAATGSLDAGALLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPALC 352

  Fly   273 RRTALRYSVAIVGLSAMAPVLDVTNYWFALETLPLNAYFAYLAYKFHEKSDSGSSRKLFRFSLIH 337
            ||.|||:.:|::.||..|||||:|.:.|.:.:||:|.|.:||.::|:..:|..||||||..||.|
Mouse   353 RRVALRHCLALIALSTAAPVLDITTWVFPVISLPINLYISYLGFRFYVDADRRSSRKLFFCSLWH 417

  Fly   338 LPALMLLFLTNKKEWYFSKPAGEENKKES 366
            ||.|:||.||.|:     :|..|.:|.|:
Mouse   418 LPLLLLLMLTCKQ-----RPGQEGDKGEA 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5037	NP_609382.1	PT_UbiA_Cox10	78..344	CDD:260120	158/265 (60%)
Cox10	NP_848466.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	68..113
Cox10	NP_848466.1	PT_UbiA_Cox10	159..414	CDD:260120	152/254 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849356
Domainoid	1	1.000	309	1.000	Domainoid score	I1327
eggNOG	1	0.900	-	-		E1_COG0109
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80170
Inparanoid	1	1.050	342	1.000	Inparanoid score	I2332
Isobase	1	0.950	-	0	Normalized mean entropy	S1699
OMA	1	1.010	-	-		QHG51964
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004321
OrthoInspector	1	1.000	-	-		oto93252
orthoMCL	1	0.900	-	-		OOG6_101203
Panther	1	1.100	-	-	LDO	PTHR43448
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R239
SonicParanoid	1	1.000	-	-		X3592
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740