DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5037 and Cox10

DIOPT Version :9

Sequence 1:	NP_609382.1	Gene:	CG5037 / 34394	FlyBaseID:	FBgn0032222	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	XP_006246895.2	Gene:	Cox10 / 691853	RGDID:	1594623	Length:	442	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	186/382 - (48%)
Similarity:	248/382 - (64%)	Gaps:	23/382 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LFKGI-RRVQSQLRTPVDLVLIRYSTAATIASQDDKGVTTAS--PVSQ-AGKVQHLPDSQITWMP 63
            |.:|: :||:.:...|...:|...|:....|..|:.....|.  |:|| ..::..|..:.|....
  Rat    64 LHRGLNQRVKPKPAPPASPLLEHTSSGQARAEVDELPPFPAPSLPLSQKPNELMELEATSIVDHS 128

  Fly    64 SPYTMPGKTLSQYK--------------KLSKFRLTSLVVITTMGGYAMAPAAFDPTTFAMCTLG 114
            .......|...|:|              :|||.:||:|||.||..|:|:||..||.:.|.:.:||
  Rat   129 LDTAKEQKEERQWKEMKLHTDDLPGILARLSKIKLTALVVSTTSAGFALAPCPFDWSCFLLTSLG 193

  Fly   115 TGLVSAAANAINQYHEVPFDSQMSRTKNRVLVTGQMTPLHAVTFAAVSATAGLSMLYFGVNGLTA 179
            |||.|.|||:|||:.||||||.|||||||.||.||::||.||:||...|..|:::|.:|||.||.
  Rat   194 TGLASCAANSINQFFEVPFDSNMSRTKNRPLVRGQISPLLAVSFATCCAVPGVALLTWGVNPLTG 258

  Fly   180 ALGAGNLFLYTTIYTPMKRISIVNTWVGSIVGAIPPLMGWAGCAATLDAGAMILAGVLYAWQFPH 244
            |||..|:||||..|||:||:||.|||||::||||||:|||.....:|||||::|.|:||:|||||
  Rat   259 ALGVFNIFLYTCCYTPLKRVSIANTWVGAVVGAIPPVMGWTAATGSLDAGALLLGGILYSWQFPH 323

  Fly   245 FNALSWNLRPDYSRAGYRMMAVTNPGLCRRTALRYSVAIVGLSAMAPVLDVTNYWFALETLPLNA 309
            ||||||.||.||||.||.||:||:|.||||.|||:.:|::.||..|||||:|.:.|.:.:||:|.
  Rat   324 FNALSWGLREDYSRGGYCMMSVTHPALCRRVALRHCLALIALSTTAPVLDITTWVFPVISLPINL 388

  Fly   310 YFAYLAYKFHEKSDSGSSRKLFRFSLIHLPALMLLFLTNKKEWYFSKPAGEENKKES 366
            |.:||.::|:..:|..||||||..||.|||.|:||.||.|:     :|..|.:|.|:
  Rat   389 YISYLGFRFYVDADRKSSRKLFFCSLWHLPLLLLLMLTCKQ-----RPGQEGDKGEA 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5037	NP_609382.1	PT_UbiA_Cox10	78..344	CDD:260120	159/265 (60%)
Cox10	XP_006246895.2	PT_UbiA_Cox10	158..413	CDD:260120	153/254 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352973
Domainoid	1	1.000	311	1.000	Domainoid score	I1279
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80170
Inparanoid	1	1.050	342	1.000	Inparanoid score	I2268
OMA	1	1.010	-	-		QHG51964
OrthoDB	1	1.010	-	-		D1260807at2759
OrthoFinder	1	1.000	-	-		FOG0004321
OrthoInspector	1	1.000	-	-		oto96795
orthoMCL	1	0.900	-	-		OOG6_101203
Panther	1	1.100	-	-	LDO	PTHR43448
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3592
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910