Protein Alignment RnrL and RNR3

DIOPT Version :10

• Sequence 1: NP_477027.1
• Gene: RnrL / 34392
• FlyBaseID: FBgn0011703
• Length: 812
• Species: Drosophila melanogaster
• Sequence 2: NP_012198.3
• Gene: RNR3 / 854744
• SGDID: S000001328
• Length: 869
• Species: Saccharomyces cerevisiae
• Alignment Length: 868
• Identity: 495/868 - (57%)
• Similarity: 640/868 - (73%)
• Gaps: 70/868 - (8%)

  Fly    12 LYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAA 76
            :||||||||:|.|.||||||||.:|.|.|:.:.:|.|.:|.::|:|:|.||||.||||||||..|
Yeast     1 MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLAAETCA 65

  Fly    77 GLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATR 141
            .:|..|||||.||||||:|||||:|.|.||.|.|||::.:|..|.:..|::|:..||:|.:|...
Yeast    66 YMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEIYNIVMENKDT 130

  Fly   142 LNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSE 206
            |||:|:|||||.|.|||||||||||||:.||::||||||::||||:||||.||::.::||||:|.
Yeast   131 LNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHGSDIESVLKTYNLMSL 195

  Fly   207 RYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGT 271
            |||||||||||.|.|..||:|||||:.|..||||||:.::::||||||:|||:||:::.||:.|:
Yeast   196 RYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAMISKTAGGVGLHINNIRSTGS 260

  Fly   272 SICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRA 336
            .|.|||||||||:||:|||||.||||||||.|||||||::|||||:|:|:|::::|..||||.||
Yeast   261 YIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALFLEPWHADIFDFVDIRKTHGKEEIRA 325

  Fly   337 RDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLW 401
            ||||.||||||||||||:.:|.|:|..|...|||.||||||||:||.:||:||| .:|:|||.||
Yeast   326 RDLFPALWIPDLFMKRVQEDGPWTLFSPSAAPGLDDVWGDEFEELYTRYEREGR-GKTIKAQKLW 389

  Fly   402 FAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFV 466
            :||::||.|||.|:|::|||||||:||||:||||.||||.||||||:|||.||||||||||..||
Yeast   390 YAILQAQTETGTPFMVYKDACNRKTNQQNLGTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFV 454

  Fly   467 TPEK-----TYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILM 526
            ...:     :|:|::|.|:.|::|.|||::||.||||:||||.||::|||:.:|:||.||..:::
Yeast   455 EVSEDGKTASYNFERLHEIAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMML 519

  Fly   527 RFPYESEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWD 591
            |.|:|||||..||:|||||||:..|||||||||.||.|.|:||||.||||||:|||:..|..:||
Yeast   520 RLPFESEEAQTLNKQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAKPFGMWD 584

  Fly   592 WQKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDL 656
            |:.|::.|..||:||||.:||||||||:||:|.||.|||.|:|:|:||||||||||||.:|||||
Yeast   585 WETLRKDIVKHGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDL 649

  Fly   657 TELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNI 721
            .:|.:|||.||..:|:..||||.:..:|.::::|||||||||.|:.|.|||||..:||||.|.|:
Yeast   650 VDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIYIDQSHSLNL 714

  Fly   722 HVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNK--------------------- 765
            .:..|:.||:||:|||.||.|||||||||||:.|:.|||||:::
Yeast   715 FLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQEVADQAATHIASVSELDRPVY 779

  Fly   766 -------------------------------KQGAVSMNGQNGTAEGS------PQKYEEDRERK 793
                                           :|.:||....|...|.|      .:..:||.:.|
Yeast   780 VPKGTKFSEQKAASALTESSDNEKDASPVPSEQSSVSSAMSNVKLEDSVAPAVPTETIKEDSDEK 844

  Fly   794 MAD------MVCSLENKDACMSC 810
            ..|      :.|:....:||.||
Yeast   845 KCDIYNEKVIACTAPTPEACESC 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RnrL	NP_477027.1	PLN02437	12..812	CDD:178056	495/868 (57%)
RNR3	NP_012198.3	PLN02437	1..775	CDD:178056	480/774 (62%)