DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RnrL and Rrm1

DIOPT Version :9

Sequence 1:	NP_477027.1	Gene:	RnrL / 34392	FlyBaseID:	FBgn0011703	Length:	812	Species:	Drosophila melanogaster
Sequence 2:	NP_001013254.1	Gene:	Rrm1 / 685579	RGDID:	1592569	Length:	792	Species:	Rattus norvegicus

Alignment Length:	806	Identity:	596/806 - (73%)
Similarity:	686/806 - (85%)	Gaps:	19/806 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAA 76
            ::|||||||||.|.|||||||||||||.||||||||..||::||.|||.||||.|||.||||.||
  Rat     1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAA 65

  Fly    77 GLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATR 141
            .||..||||||||||||||||||||||.||||.|||||::|....:..|:|:.....:|..:..|
  Rat    66 TLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLEIVMAHKDR 130

  Fly   142 LNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSE 206
            |||:|||||||.||||||||||||||||.|||:|||||||||||::|||.||||||:||||||||
  Rat   131 LNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSE 195

  Fly   207 RYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGT 271
            ::|||||||||.|.||||||||||||:|..||||||:.:::|||:|||||||||:.|.||||.|:
  Rat   196 KWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGS 260

  Fly   272 SICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRA 336
            .|.||||.||||||||||:||.||||||||.||||||||||||||.|:||||:|||||||||.||
  Rat   261 YIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRA 325

  Fly   337 RDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLW 401
            ||||:|||||||||||||.|.|||||||::||||.:|||:|||||||.||::||..:.||||.||
  Rat   326 RDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLW 390

  Fly   402 FAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFV 466
            :||||:|.|||.||||:||:|||||||||:|||||||||||||||::.||:|||||||:||||:|
  Rat   391 YAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYV 455

  Fly   467 TPEKTYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYE 531
            |||.||||:||.||||::.:||||||||||||:|||..||.||||:|||:||.|||.||||:|:|
  Rat   456 TPEHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFE 520

  Fly   532 SEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDWQKLK 596
            |.||.|||:|||||||||||||||:||:..|||||||||||||||||||||:..||:||||:.||
  Rat   521 SPEAQLLNKQIFETIYYGALEASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPTDLWDWKLLK 585

  Fly   597 ESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDLTELDL 661
            |.|..:|:|||||:|||||||||||:|||||.||||:|||||||||||||:||.|||:||||..|
  Rat   586 EKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGL 650

  Fly   662 WDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNIHVAEP 726
            |:::||||||:..||||:|..||..::.|||||||||.|:.:||||:||||||||||.|||:|||
  Rat   651 WNEEMKNQIIACNGSIQSIPEIPEDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEP 715

  Fly   727 NYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNK-----KQGAVSMNGQNGTAEGSPQKY 786
            |||||||:|||.||.|||||||||||:||||.||||:||     |:.|:              |.
  Rat   716 NYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKAL--------------KE 766

  Fly   787 EEDRERKMADMVCSLENKDACMSCGS 812
            ||::||..|.|||||||::.|:.|||
  Rat   767 EEEKERNTAAMVCSLENREECLMCGS 792

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RnrL	NP_477027.1	PLN02437	12..812	CDD:178056	594/804 (74%)
Rrm1	NP_001013254.1	PLN02437	1..792	CDD:178056	594/804 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354180
Domainoid	1	1.000	861	1.000	Domainoid score	I54
eggNOG	1	0.900	-	-		E1_COG0209
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H806
Inparanoid	1	1.050	1234	1.000	Inparanoid score	I168
OMA	1	1.010	-	-		QHG62381
OrthoDB	1	1.010	-	-		D156716at2759
OrthoFinder	1	1.000	-	-		FOG0003792
OrthoInspector	1	1.000	-	-		oto98027
orthoMCL	1	0.900	-	-		OOG6_100448
Panther	1	1.100	-	-	LDO	PTHR11573
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2647
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810