Protein Alignment RnrL and cdc22

DIOPT Version :10

• Sequence 1: NP_477027.1
• Gene: RnrL / 34392
• FlyBaseID: FBgn0011703
• Length: 812
• Species: Drosophila melanogaster
• Sequence 2: NP_594491.1
• Gene: cdc22 / 2541695
• PomBaseID: SPAC1F7.05
• Length: 811
• Species: Schizosaccharomyces pombe
• Alignment Length: 820
• Identity: 535/820 - (65%)
• Similarity: 661/820 - (80%)
• Gaps: 28/820 - (3%)

  Fly    12 LYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNLAAEIAA 76
            ::|.|||||||:|.|||||:|:.:|||.|:.|.||||.||.:||:|:|.||||.||||||||.||
pombe     1 MFVYKRDGRQEKVAFDKITARVSRLCYGLDSDHVDPVEITQKVISGVYPGVTTIELDNLAAETAA 65

  Fly    77 GLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEFHYNVVKKNATR 141
            .:|..||||||||||||||||||:|:|.||.|.:.|:::||.:|::..|::|:..|::|.|:...
pombe    66 TMTTKHPDYAILAARIAVSNLHKQTEKVFSTVVQQLHDYVNPKTDKPAPMISDKIYDIVMKHKDE 130

  Fly   142 LNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIHGEDIDAAVETYNLLSE 206
            |:|:|||||||.||:||||||||||||:.:||:|||||||:||||:|||||||:||:|||||:|:
pombe   131 LDSAIIYDRDFTYNFFGFKTLERSYLLRIDGKVAERPQHMIMRVAVGIHGEDIEAAIETYNLMSQ 195

  Fly   207 RYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGT 271
            |||||||||||.|.|.|||||||||:||..||||||:.:::.||||||:|||||:|:|.|||.|:
pombe   196 RYFTHASPTLFNAGTPRPQLSSCFLVTMKDDSIEGIYDTLKMCAMISKTAGGIGINIHNIRATGS 260

  Fly   272 SICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRA 336
            .|.||||||||:|||:||:||.||||||||.|||||||.||||||:||.:||||:|..|.|:.||
pombe   261 YIAGTNGTSNGIVPMIRVYNNTARYVDQGGNKRPGAFAAYLEPWHADVMDFLELRKTHGNEDFRA 325

  Fly   337 RDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVWGDEFEKLYEKYEQEGRANRTVKAQSLW 401
            |::|||||||||||:|||.|..|:..||::.|||.|||||||..||||||:|.|..|::.||.:|
pombe   326 REMFYALWIPDLFMQRVERNEQWTFFCPNEAPGLADVWGDEFVALYEKYEKENRGRRSLPAQKVW 390

  Fly   402 FAIIEAQVETGNPYMLFKDACNRKSNQQNVGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFV 466
            :||:::|||||||:||:||:|||||||:|||||:||||||||||||:|||:|||||||:||..|:
pombe   391 YAILQSQVETGNPFMLYKDSCNRKSNQKNVGTIRCSNLCTEIVEYSSPDEVAVCNLASVALPTFI 455

  Fly   467 TPEKTYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYE 531
            ...| |:|:||.:|.|:||:|||||||:||||:||||:||:||||||:|:||.|||...:|.|:|
pombe   456 KDGK-YNFQKLHDVVKVVTRNLNKIIDVNYYPVPEARRSNMRHRPVGLGVQGLADAFFALRLPFE 519

  Fly   532 SEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWDWQKLK 596
            |..|..||.|||||||:.|||||||:||.||.||:|||||.|:||||||||:..||:||||.:||
pombe   520 SAGAKKLNIQIFETIYHAALEASCEIAQVEGTYESYEGSPASQGILQYDMWNVNPTDLWDWAELK 584

  Fly   597 ESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHHLLRDLTELDL 661
            |.|..||:||||||||||||||:||:|.||.|||||:|:|.|||||||||:||..||:||.|.||
pombe   585 EKIAKHGIRNSLLVAPMPTASTSQILGFNECFEPYTSNMYQRRVLSGEFQIVNPWLLKDLVERDL 649

  Fly   662 WDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGAFIDQSQSFNIHVAEP 726
            |::||||:::...||||.|..||..::||||||||||.|:.|..|||||.|||||||.|||:.:|
pombe   650 WNEDMKNKLVMLDGSIQAIPEIPQDLKDLYKTVWEISQKTVIDYAADRGPFIDQSQSLNIHLKDP 714

  Fly   727 NYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTV---------------NKKQGAVSMNGQN 776
            :|||:||:|||.||.|||||||||||..|:.||:|||               |||...     :|
pombe   715 SYGKITSMHFYGWKKGLKTGMYYLRTMAASAAIKFTVDPVALRARNEESNEENKKPVI-----KN 774

  Fly   777 GTAE--GSPQKYEED--RERKMADMVCSLENKDACMSCGS 812
            |.||  ..|.|.|.|  .|:.:|   ||::|.:||..|.:
pombe   775 GKAEISAEPTKEEIDIYNEKVLA---CSIKNPEACEMCSA 811

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RnrL	NP_477027.1	PLN02437	12..812	CDD:178056	535/818 (65%)
cdc22	NP_594491.1	PLN02437	1..811	CDD:178056	535/818 (65%)