DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4995 and SLC25A2

DIOPT Version :10

Sequence 1:NP_609380.1 Gene:CG4995 / 34390 FlyBaseID:FBgn0032219 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_114153.1 Gene:SLC25A2 / 83884 HGNCID:22921 Length:301 Species:Homo sapiens


Alignment Length:279 Identity:88/279 - (31%)
Similarity:131/279 - (46%) Gaps:23/279 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 VDFVAGLLGGAAGVLVGHPFDTVKVHLQTDDPRNPKYKGTFHCFRTIVQRDKFIGLYRGISSPMG 106
            :|..||..||.|.||.|.||||:||.:||..   ..|||...||.....:....|.|:|....:.
Human    11 IDLTAGAAGGTACVLTGQPFDTIKVKMQTFP---DLYKGLTDCFLKTYAQVGLRGFYKGTGPALM 72

  Fly   107 GIGLVNAIVFGVYGNVQRL-----SNDPNSLTSHF---FAGSIAGVAQGFVCAPMELAKTRLQLS 163
            .....|:::|..||..|:.     ..|..:..|..   .|||.|.........|.||.|.|||..
Human    73 AYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKCRLQTM 137

  Fly   164 TQVDSGIKFTGPIHCL----KYIVKTEGIRGAFKGLTATILRDIPGFASYFVSFEYLM------R 218
            .:::...|.....:.:    |.|:|.:|..|.:.||::|:|:::||:..:|..:|...      |
Human   138 YEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYFFFFGGYELSRSFFASGR 202

  Fly   219 QVETPGVAYTLMAGGCAGMSSWLACYPIDVVKTHMQADALGANAKYNGFIDCAMKGFRNEGPQYF 283
            ..:..|..:.:::||.||:..||..:|:|.:|:.:|  .|....|..|||...:...||||....
Human   203 SKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQ--VLSMYGKQAGFIGTLLSVVRNEGIVAL 265

  Fly   284 FRGLNSTLIRAFPMNAACF 302
            :.||.:|:|||.|.|.|.|
Human   266 YSGLKATMIRAIPANGALF 284

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4995NP_609380.1 Mito_carr 36..125 CDD:395101 30/82 (37%)
Mito_carr 128..218 CDD:395101 27/102 (26%)
Mito_carr 221..304 CDD:395101 30/82 (37%)
SLC25A2NP_114153.1 Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 7..91 30/82 (37%)
Mito_carr 9..94 CDD:395101 30/85 (35%)
Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 104..197 26/92 (28%)
Mito_carr <125..198 CDD:395101 21/72 (29%)
Mito_carr 205..296 CDD:395101 30/82 (37%)
Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 207..293 30/80 (38%)

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