DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4995 and slc25a20

DIOPT Version :9

Sequence 1:	NP_609380.1	Gene:	CG4995 / 34390	FlyBaseID:	FBgn0032219	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_989099.1	Gene:	slc25a20 / 394703	XenbaseID:	XB-GENE-971451	Length:	301	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	104/288 - (36%)
Similarity:	156/288 - (54%)	Gaps:	28/288 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ETFSPKMVVDFVAGLLGGAAGVLVGHPFDTVKVHLQTDDPR-----NPKYKGTFHCFRTIVQRDK 93
            :..||  :.:|.||..||...|..|||.||:||.:|| .|:     .|.|.|||.||:..:..:.
Frog     6 QPISP--MKNFFAGGFGGICLVFAGHPLDTIKVRIQT-QPKPVPGIPPLYSGTFDCFKKTLVNEG 67

  Fly    94 FIGLYRGISSPMGGIGLVNAIVFGVYGNVQRL-SNDPNSLTSH---FFAGSIAGVAQGFVCAPME 154
            ..|||:|:::|:.|:..:.|:.|..:|..::| ...|..:.::   |.||.::||....:.||.|
Frog    68 LRGLYKGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDILTYPQLFAAGMLSGVFTTAIMAPGE 132

  Fly   155 LAKTRLQLSTQVDSG-IKFTGPIHCLKYIVKTEGIRGAFKGLTATILRDIPGFASYFVSFEYLMR 218
            ..|..||:  |..|| :|:.||:.|.|.:.:..||||.:||...|::||:|....||:::|:| :
Frog   133 RIKCLLQI--QAASGEVKYAGPMDCAKQLYREAGIRGIYKGTVLTLMRDVPASGMYFMTYEWL-K 194

  Fly   219 QVETP--------GVAYTLMAGGCAGMSSWLACYPIDVVKTHMQADALGANAKY-NGFIDCAMKG 274
            .:.||        .|...|.|||.||:.:|....|.||:|:..|....|   || |||.|...:.
Frog   195 NILTPEGHSVSELSVPKILFAGGMAGIFNWAVAIPPDVLKSRFQTAPAG---KYPNGFRDVLREL 256

  Fly   275 FRNEGPQYFFRGLNSTLIRAFPMNAACF 302
            .|.||....::|..:.::||||.|||||
Frog   257 IREEGIGSLYKGFTAVMLRAFPANAACF 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4995	NP_609380.1	Mito_carr	36..125	CDD:278578	34/93 (37%)
		PTZ00169	41..295	CDD:240302	94/272 (35%)
		Mito_carr	128..218	CDD:278578	34/93 (37%)
		Mito_carr	221..304	CDD:278578	35/91 (38%)
slc25a20	NP_989099.1	Mito_carr	8..102	CDD:365909	35/96 (36%)
		Mito_carr	108..198	CDD:365909	33/92 (36%)
		Mito_carr	207..294	CDD:365909	33/81 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54095
OrthoDB	1	1.010	-	-		D1072378at2759
OrthoFinder	1	1.000	-	-		FOG0000326
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1756
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.960