DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4995 and slc25a45

DIOPT Version :9

Sequence 1:	NP_609380.1	Gene:	CG4995 / 34390	FlyBaseID:	FBgn0032219	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_002662242.1	Gene:	slc25a45 / 100329446	-ID:	-	Length:	284	Species:	Danio rerio

Alignment Length:	284	Identity:	110/284 - (38%)
Similarity:	158/284 - (55%)	Gaps:	18/284 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VDFVAGLLGGAAGVLVGHPFDTVKVHLQTDDPRNPKYKGTFHCFRTIVQRDKFIGLYRGISSPMG 106
            |:|:||.:.||.|::||||.|||||.|||..    .|.|...|......|:...|.::|:|.|:.
Zfish     4 VEFIAGWISGAVGLVVGHPLDTVKVRLQTQS----VYGGILDCVIKTYTREGLHGFFKGMSFPVL 64

  Fly   107 GIGLVNAIVFGVYGN-----VQRLSNDPNS---LTSHFFAGSIAGVAQGFVCAPMELAKTRLQLS 163
            .:.:.||:.||.|.|     .|...||.:.   |:..|.||..:|:||.||.||::|.|.|||..
Zfish    65 SVAVSNAVAFGSYSNALDYLTQSHHNDHSQRSPLSYVFMAGCFSGLAQLFVTAPIDLVKVRLQNQ 129

  Fly   164 TQVDS-GIKFTGPIHCLKYIVKTEGIRGAFKGLTATILRDIPGFASYFVSFEYLMRQV----ETP 223
            |:..| |.|:.||:||:..||:.:|::|.|:|..|..|||:|.:..||:.:|:.:|.:    :.|
Zfish   130 TRSRSAGNKYRGPLHCVAVIVREDGLKGLFRGFWALALRDVPCYGLYFLPYEFTLRMMTEKGKQP 194

  Fly   224 GVAYTLMAGGCAGMSSWLACYPIDVVKTHMQADALGANAKYNGFIDCAMKGFRNEGPQYFFRGLN 288
            |....|.|||.||:.:|....|:||||..:|... |....|:|.::|.....|.||.:.||:||.
Zfish   195 GHCAVLAAGGVAGVITWACATPMDVVKARLQMSG-GGGRVYSGVLNCITVSVREEGIRVFFKGLL 258

  Fly   289 STLIRAFPMNAACFFVVSWVLDIC 312
            ...:||||:||..|.....:|..|
Zfish   259 LNSVRAFPVNAVTFLSYEMILRAC 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4995	NP_609380.1	Mito_carr	36..125	CDD:278578	34/87 (39%)
		PTZ00169	41..295	CDD:240302	102/265 (38%)
		Mito_carr	128..218	CDD:278578	39/93 (42%)
		Mito_carr	221..304	CDD:278578	33/82 (40%)
slc25a45	XP_002662242.1	Mito_carr	2..85	CDD:278578	33/84 (39%)
		Mito_carr	94..191	CDD:278578	39/96 (41%)
		Mito_carr	200..280	CDD:278578	31/80 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I8495
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1072378at2759
OrthoFinder	1	1.000	-	-		FOG0000326
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X353
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920