DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4972 and AT3G44330

DIOPT Version :9

Sequence 1:	NP_609378.1	Gene:	CG4972 / 34388	FlyBaseID:	FBgn0032217	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_190019.1	Gene:	AT3G44330 / 823558	AraportID:	AT3G44330	Length:	565	Species:	Arabidopsis thaliana

Alignment Length:	597	Identity:	160/597 - (26%)
Similarity:	278/597 - (46%)	Gaps:	96/597 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IFRGGLPHCLLIVFSLLLTCSPVMPSE--FEVISMSKYDLNGQHYGSRVASISLEARSL---YSW 70
            :|....|  :|.:..:|:.|..:..:.  .:|..:.:||::|..:|||.:|::..|.||   ...
plant    15 VFESMYP--ILALMLILVACVELCDAATVVDVYRLIQYDISGVPFGSRFSSLNHHAASLSFQRGA 77

  Fly    71 NTSRHCVLTRLTDLSI---HDFDKLRQGAGGLILMLPANIL-------NLDPET---KELITILE 122
            :.||..::..|.:|.|   .|:...:|..|||:::||....       :|..|.   :.|:..||
plant    78 DLSRSVLILPLRELDIAFVQDYISQKQSLGGLLILLPQTFRPGNVGGGSLSSENDGFRSLLGQLE 142

  Fly   123 QSMLTHTAAVPIYFAPYNKDLEKIIDDITYTTTDSPGQNQTALA---QLVVTVSANRYHINVGGG 184
            :.::......|:|||..|::.:.::.|:  ...|:.||..||..   :||::||..|   .:...
plant   143 KLLVHGNIPFPVYFAFENEETDAMLADV--KKNDALGQQATATTGGYKLVISVSEPR---KIASP 202

  Fly   185 SIAANKNSKIPIIHGELIPNQLALKPTESVADGQKLPVILITANLKTFGIYNDYPVNADA----- 244
            :| .|....:|.:..|              .|..:||.|.:.|:..|||......|.:|:
plant   203 TI-TNIQGWLPGLRAE--------------GDSSQLPTIAVVASYDTFGAAPALSVGSDSNGSGV 252

  Fly   245 AVLLVLMELFSKLHYTSSMAPKYRLRFLLSDAGVLLNFQGSKKWLE-VDDNALQNVEFVLCLDTI 308
            ..||.:..|||.|:.......||.|.|.|:..|. .|::|::|||: :|....:::::.:||:::
plant   253 VALLEVARLFSVLYSNPKTRGKYNLLFALTSGGP-YNYEGTQKWLKSLDQRMRESIDYAICLNSV 316

  Fly   309 SESLSYTTENALYMHVSKPPKDKTSISNFFKLLKSSAEKYSNGLAVEGVHKKINLADTKLAWEHE 373
            .   |:.:|  |.:|||||| |...|...|:...:.||..  |..|...|||||::::::|||||
plant   317 G---SWDSE--LLIHVSKPP-DNAYIKQIFEGFSNVAEDL--GFQVALKHKKINISNSRVAWEHE 373

  Fly   374 RFSIKRYPSFTLSSVKSPRSPIRTTIFKNDESRLV--EHTLNTTRIIAEALASFMY-KVDPTSSI 435
            :||..|..:.|||.:.:|...:......:|..:||  :..:...:::||:||..:| .......|
plant   374 QFSRLRVTAATLSELSTPPELLENAGSLSDTRQLVNEDAIIKGVKLVAESLAKHIYGHQGKDIKI 438

  Fly   436 F--EGQLAIKEENILPYF------------GVKSILHNND-----VKDAFEKYLNNVKIIYDKPD 481
            |  :..||:.     |::            .|...|..|:     :|...|.|...|.:   :.:
plant   439 FADDSSLAVN-----PFYVRSWLDLLSQTPRVAPFLSKNEPLIMALKKELEDYTAEVSV---QHE 495

  Fly   482 ARDPEFMFYNENEVKLNVYRVKPAIFDLFLTFVIGAYLLAVFLAIQYFPRFYDEVSKLTKEDPAG 546
            :.|..|.||:..:..||:|:|....|||.|..|:|:||:.:|..:....|..|::..|.:..|
plant   496 SLDGSFTFYDSTKASLNIYQVASVTFDLLLLLVLGSYLIVLFSFLVITTRGLDDLISLFRRPP-- 558

  Fly   547 QSNGHSSERVRM 558
                  |.:|:|
plant   559 ------SRKVKM 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4972	NP_609378.1	M28_nicalin_like	121..429	CDD:193503	93/319 (29%)
AT3G44330	NP_190019.1	M28_nicalin_like	138..431	CDD:349878	93/321 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2526
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10604
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1529
OMA	1	1.010	-	-		QHG60111
OrthoDB	1	1.010	-	-		D424149at2759
OrthoFinder	1	1.000	-	-		FOG0004762
OrthoInspector	1	1.000	-	-		oto3292
orthoMCL	1	0.900	-	-		OOG6_104880
Panther	1	1.100	-	-	LDO	PTHR31826
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3350
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840