Protein Alignment CG4972 and Ncln

DIOPT Version :9

• Sequence 1: NP_609378.1
• Gene: CG4972 / 34388
• FlyBaseID: FBgn0032217
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001014104.1
• Gene: Ncln / 314648
• RGDID: 1309355
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 584
• Identity: 204/584 - (34%)
• Similarity: 300/584 - (51%)
• Gaps: 73/584 - (12%)

  Fly     1 MMNEADSLTE-IFRGGLPHCL---LIVF--SLLLTCSPVMPS-----EFEVISMSKYDLNGQHYG 54
            |:.||..:.| :.:..   ||   .|||  ::||..:|.:|:     ||.|..|.:|||.||.||
  Rat     1 MLEEAGEVLENVLKAS---CLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYG 62

  Fly    55 SRVASISLEARSLYSWNTSRHCVLTRLTDLSIHDFDK-LRQGAGGLILMLPANILNLDPETKELI 118
            :|.|.::.|||::.:...||.|||.||.|.|...:.| |||.||.::::||..:..:..:.....
  Rat    63 TRNAVLNTEARTVDADVLSRRCVLMRLLDFSYEHYQKALRQSAGAVVIILPRAMAAVPQDVVRQF 127

  Fly   119 TILEQSMLTHTAAVPIYFAPYNKDLEKIIDDITYTTTDSPGQNQTALAQLVV-TVSANRYHINVG 182
            ..:|..||.....||:|||..::.|..|.:.   |...|..|...:.|:::: |.:||.:.:...
  Rat   128 MEIEPEMLAMETVVPVYFAVEDEALLSIYEQ---TQAASASQGSASAAEVLLHTATANGFQMVTS 189

  Fly   183 GGSIAANKNSKIPIIHGELIPNQLALKPTESVADGQKLPVILITANLKTFGIYNDYPVNADA--- 244
            |....|..:..|..:.|.|           :...|:.||.|:|.|:...||:.....:.||:
  Rat   190 GAQSQAVSDWLITSVEGRL-----------TGLGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGS 243

  Fly   245 --AVLLVLMELFSKLHYTSSMAPKYRLRFLLSDAGVLLNFQGSKKWLE-----VDDNALQ-NVEF 301
              :|||.|..|||:|:........|.|.|..|..| ..|:||:|:|||     .|.:.|| ||.|
  Rat   244 GISVLLELARLFSRLYTYKRTHAAYNLLFFASGGG-KFNYQGTKRWLEDSLDHTDSSLLQDNVAF 307

  Fly   302 VLCLDTISESLSYTTENALYMHVSKPPKDKTSISNFFKLLKSSAEKYSNGLAVEGVHKKINLADT 366
            ||||||:...      :.|.:||||||::.|....|.:.|:..|......::...|||||||||.
  Rat   308 VLCLDTVGRG------SHLRLHVSKPPREGTLQHVFLRELEMVAAHQFPDVSFSMVHKKINLADD 366

  Fly   367 KLAWEHERFSIKRYPSFTLSSVKSPRSPIRTTIFKNDESRLVEHTL-NTTRIIAEALASFMYKV- 429
            .||||||||:|:|.|:||||.:::.|:..|::|. :..||:...|| ..||||||||...:|.:
  Rat   367 VLAWEHERFAIRRLPAFTLSHLENHRAGPRSSIM-DVRSRVDSKTLTRNTRIIAEALTRVIYNLT 430

  Fly   430 ----DPTSSIFEGQLAIKEENILPYFGVKSILHN---------------NDVKDAFEKYLNNVKI 475
                .|...:|..|:.:::|.|   ..|...|.|               :.::....:||.:|:.
  Rat   431 EKGTPPDMPVFTEQMQVQQEQI---DSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQ 492

  Fly   476 IYDKPDARDPEFMFYNENEVKLNVYRVKPAIFDLFLTFVIGAYLLAVFLAIQYFPRFYDEVSKL 539
            .:.|.|.|||||:||::.:..:|.||||||||||.|...|||||...:.|:|:|...|..|.:|
  Rat   493 HHVKADKRDPEFVFYDQLKQVMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4972	NP_609378.1	M28_nicalin_like	121..429	CDD:193503	115/320 (36%)
Ncln	NP_001014104.1	M28_nicalin_like	130..429	CDD:193503	115/320 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2526
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10604
Inparanoid	1	1.050	269	1.000	Inparanoid score	I2944
OMA	1	1.010	-	-		QHG60111
OrthoDB	1	1.010	-	-		D355092at33208
OrthoFinder	1	1.000	-	-		FOG0004762
OrthoInspector	1	1.000	-	-		oto96207
orthoMCL	1	0.900	-	-		OOG6_104880
Panther	1	1.100	-	-	LDO	PTHR31826
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3350
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770