Protein Alignment CG4972 and nra-2

DIOPT Version :9

• Sequence 1: NP_609378.1
• Gene: CG4972 / 34388
• FlyBaseID: FBgn0032217
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001122514.1
• Gene: nra-2 / 172803
• WormBaseID: WBGene00011488
• Length: 563
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 148/585 - (25%)
• Similarity: 246/585 - (42%)
• Gaps: 113/585 - (19%)

  Fly     6 DSLTEIFRGGLPHCLLIVFSLLLT-C--------SPVMPSEFEVISMSKYDLNGQHYGSRVASIS 61
            |.:.:.||.   ..||...:|:|| |        ..|:.:||....:.:|:::|..||.:...:|
 Worm     3 DEIIDFFRS---PALLFYMTLMLTICVVNGSQQVGEVVETEFHAYRLHQYEISGNIYGCKNYRVS 64

  Fly    62 LEARSLYSWNTSRHCVLTRLTDLSIHDFDKL-RQGAGGLILMLPANILNLDPETKELITILEQSM 125
            .||.||.: .|.|..::|...||...|.|.: ....|.:::.:|.|:..|:...::....||..:
 Worm    65 YEAVSLGA-RTLRRTMVTTWRDLLTTDVDDMWALSTGAVLIFIPDNLDELNDIDRKAFIDLEAKL 128

  Fly   126 LTHTAAVPIYFAPYNKDLEKIIDDITYTTTDSPGQNQTALAQLVVTVSANRYHINVGGGSIAANK 190
            |:....:.:|.||:|.|...|:.|:...:..:|    |||..|:.::|         |.:|:...
 Worm   129 LSAKTDLAVYVAPFNDDAVSILHDVNTRSEKAP----TALQHLLQSLS---------GNTISITS 180

  Fly   191 NSKIPIIHGELIPNQLALKPTESVADGQK-LPVILITANLKTFGIYNDYPVNADA-----AVLLV 249
            :.:.|    ||.|:...|.....::.|.: .|.|...|:..|..........||:     ..||.
 Worm   181 SDQSP----ELPPSYKPLNIVGRLSSGDRAAPTIAFVAHYDTQSAVPGVSPGADSNGSGIVALLE 241

  Fly   250 LMELFSKLHYTSSMAPKYRLRFLLSDAGVLLNFQGSKKWLE---------------------VDD 293
            |:.:.||.:.:.|..|.|.:.|:.:.|| .||:||::.|::                     .||
 Worm   242 LLAVLSKFYDSPSTRPPYNILFIWTAAG-KLNYQGTRHWIDEYQKGFDSADYAKSGLSRKGFSDD 305

  Fly   294 NALQNVEFVLCLDTISESLSYTTENALYMHVSKPPKDKTSISNFFKLLK--SSAEKYSNGLAVEG 356
                .|:..:|::.|...     ....:||..|.|.:.:..:...:.||  ||.....|   :|.
 Worm   306 ----RVDLAICIEAIGRK-----TGGFFMHAGKTPSENSVAAQLLRRLKYFSSISPKKN---IEL 358

  Fly   357 VHKKINLADTKLAWEHERFSIKRYPSFTLSSVKSPRSPIRTTIF----KNDESRLVEHTLNTTRI 417
            |.|||:|. |..|||||:|:|||.|:.|||::.||..|.|.:|.    ..||..|:::    .|:
 Worm   359 VTKKISLT-TVSAWEHEKFNIKRMPAITLSTLPSPSDPARNSILDLPSALDEDELIDN----IRL 418

  Fly   418 IAEALASFMYKV---DPTSSI---------------------FEGQLAIKEENILPYFGVKSILH 458
            |.||:..::..:   .|:|..                     |..|.|.:...:......:||..
 Worm   419 IGEAVLGYILDLPESGPSSDSRVKSEATMLSKDAVDKQRVHHFIRQFASRPRPVGDQRATESITS 483

  Fly   459 NNDVKDAFEKYLNNVKIIYDKPDARDPEFMFYNENEVKLNVYRVKPAIFDLFLTFVIGAYLLAVF 523
            |  :......|.|..|......||:     .:...:.:|...|||||:|:|.:...:..||.|.:
 Worm   484 N--LASVAAGYGNVFKSAVTITDAK-----AFGVTQNRLVAERVKPAVFELVIAAGVFTYLSAFY 541

  Fly   524  523
             Worm   542  541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4972	NP_609378.1	M28_nicalin_like	121..429	CDD:193503	92/340 (27%)
nra-2	NP_001122514.1	M28_nicalin_like	121..430	CDD:349878	92/343 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156566
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10604
Inparanoid	1	1.050	138	1.000	Inparanoid score	I3116
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60111
OrthoDB	1	1.010	-	-		D355092at33208
OrthoFinder	1	1.000	-	-		FOG0004762
OrthoInspector	1	1.000	-	-		oto19309
orthoMCL	1	0.900	-	-		OOG6_104880
Panther	1	1.100	-	-	LDO	PTHR31826
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3506
SonicParanoid	1	1.000	-	-		X3350
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.940