Protein Alignment Usp14 and UBP6

DIOPT Version :10

• Sequence 1: NP_609377.1
• Gene: Usp14 / 34387
• FlyBaseID: FBgn0032216
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_116665.1
• Gene: UBP6 / 850562
• SGDID: S000001906
• Length: 499
• Species: Saccharomyces cerevisiae
• Alignment Length: 511
• Identity: 159/511 - (31%)
• Similarity: 255/511 - (49%)
• Gaps: 69/511 - (13%)

  Fly     4 FKVKVKWGRELYTDIVVNTDEEPILFKAQLFALTGVQPDRQKVMCKGGILKDDQWNLQ--IKDGA 66
            |:..::...::| .|.::||......|::...||.|...|||.|.|||:..::...:.  ||.|:
Yeast     6 FEFNIRHSGKVY-PITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEESIKIYPLIKPGS 69

  Fly    67 VVLLLGSKE-SVPEVPATPVKFIEDM-NEAEAATAMRLPAGLTNLGNTCYMNATVQCLNAVPELR 129
            .|:|||:.: ::...||....||||: .|.:.....:||.|..|:|||||:|||:|.|..|.:||
Yeast    70 TVMLLGTPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLR 134

  Fly   130 TALSTF------SNDGTDTMSTAFSISSAMKSIFAQMEKGT--TVTPIVLLQALHRASPQFAQ-T 185
            ..:..:      ||.|.........|...||..|..::..:  :|.|||||..|.:..||||: .
Yeast   135 DMILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERD 199

  Fly   186 GENGTYRQQDANECWAEILKMLQQKLRPKNQEPSNTVQKRHSS---FIDQF---FGGTFEVKMSS 244
            .:.|.|:||||.|.:.::.                     ||.   |.|:|   |...|:..:..
Yeast   200 SQGGFYKQQDAEELFTQLF---------------------HSMSIVFGDKFSEDFRIQFKTTIKD 243

  Fly   245 EEDPDEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSETLGRDAKYIRTYLVSRLPA 309
            ..:.::.:...:|:..:|.|.||....:|::||...:.|::.|:|:..|.::.|.....:||||.
Yeast   244 TANDNDITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPK 308

  Fly   310 YLTVQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPELQNKLCPMRSKFKDLEDKKMEVD-V 373
            :||||:|||.:|......:|:|:.:.||...|..::.|||...:...:|.:.:.:|.:|.|.: .
Yeast   309 FLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKNEKERE 373

  Fly   374 VKRN--EP-------------------NEEKKDVKYEQF--WFDDDL--GSNNSGYYTLQAVLTH 413
            :||.  :|                   ||.:||...|::  .|..:|  |.|.|..|.|..|:||
Yeast   374 IKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYNLIGVITH 438

  Fly   414 KGRSSSSGHYVAWVRSSGD--VWFKFDDDEVSAVATDEILRLSGGGDWHCAYVLLY 467
            :|.:|.||||.|::|...|  .|:||:||:||.|..::|..|:|||:...|.:|:|
Yeast   439 QGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALILMY 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp14	NP_609377.1	Ubl_USP14_like	4..75	CDD:340521	23/72 (32%)
		Peptidase_C19A	105..467	CDD:239122	126/404 (31%)
UBP6	NP_116665.1	Ubl1_cv_Nsp3_N-like	5..78	CDD:475130	23/72 (32%)
		Peptidase_C19A	110..495	CDD:239122	127/406 (31%)