DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp14 and AT4G22350

DIOPT Version :9

Sequence 1:	NP_001260321.1	Gene:	Usp14 / 34387	FlyBaseID:	FBgn0032216	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001190799.1	Gene:	AT4G22350 / 828330	AraportID:	AT4G22350	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	386	Identity:	89/386 - (23%)
Similarity:	144/386 - (37%)	Gaps:	96/386 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LP--AGLTNLGNTCYMNATVQCLNAVPELRTALSTFSNDGTDTMSTAFSISSAMKSIF-AQMEKG 163
            ||  .||.|:..|.::|.|:|.|..|..||.......|................:.|: |:..||
plant   225 LPGMVGLNNIQKTEFVNVTIQSLMRVTPLRNFFLIPENYQHCKSPLGHRFGELTRKIWHARNFKG 289

  Fly   164 TTVTPIVLLQALHRASPQFAQTGENGTYRQQDANECWAEILKMLQQKLRPKNQEPSNTVQKRHSS 228
             .|:|...|||:.:||.:..:.|:     |.|..|..:.:|..|...||         ..|..||
plant   290 -QVSPHEFLQAVMKASKKRFRIGQ-----QSDPVEFMSWLLNTLHMDLR---------TSKDASS 339

  Fly   229 FIDQFFGGTFEVKMSSEEDPDEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKE----QLVKK- 288
            .|.:.|.|  |:::..|...:|...::...||.|...:.....:.....|:.:.:    .|:||
plant   340 IIHKCFQG--ELEVVKEYQGNENKEISRMPFLMLGLDLPPPPLFKDVMEKNIIPQVALFDLLKKF 402

  Fly   289 -SETLGRDAKYIR------TYLVSRLPAYLTVQFVRFQ----YKGKEGINAKVLKDIKFPIDFDA 342
             .||:   .:.:|      .|.|.:.|.||....|||:    :|.|   |..:   :.||:
plant   403 DGETV---TEVVRPKLARMRYRVIKSPRYLMFHMVRFKKNNFFKEK---NPTL---VNFPV---- 454

  Fly   343 FELCTPELQNKLCPMRSKFKDLEDKKMEVDVVKRNEPNEEKKDVKYEQFWFDDDLGSNNSGYYTL 407
                               ||:|.:.....:.:..|                   |.|....|.|
plant   455 -------------------KDMELRDYIPSLPRAPE-------------------GENVCSKYNL 481

  Fly   408 QAVLTHKGRSSSSGHYVAWV-RSSGDVWFKFDDDEVSAVATDEILRLSGGGDWHCAYVLLY 467
            .|.:.|.|: ...|::..:| |.|.::|::..|..| |....:::.||.      ||:.:|
plant   482 IANIVHDGK-PEDGYFRVFVQRKSQELWYEMQDLHV-AETLPQMVELSE------AYMQIY 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp14	NP_001260321.1	UBQ	4..73	CDD:214563
		UBQ	5..73	CDD:294102
		UCH	103..467	CDD:278850	87/383 (23%)
		Peptidase_C19A	105..467	CDD:239122	86/379 (23%)
AT4G22350	NP_001190799.1	Peptidase_C19M	110..535	CDD:239134	89/386 (23%)
AT4G22350	NP_001190799.1	UCH	229..534	CDD:278850	86/380 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910