DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Usp14 and Usp47

DIOPT Version :10

Sequence 1:NP_609377.1 Gene:Usp14 / 34387 FlyBaseID:FBgn0032216 Length:475 Species:Drosophila melanogaster
Sequence 2:NP_523937.2 Gene:Usp47 / 38644 FlyBaseID:FBgn0016756 Length:1556 Species:Drosophila melanogaster


Alignment Length:463 Identity:102/463 - (22%)
Similarity:171/463 - (36%) Gaps:127/463 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 VPATPVKFIEDM---NEAEAATAMRLP---AGLTNLGNTCYMNATVQCLNAVPELRTALS--TFS 136
            |..|...|:...   .||||..|...|   .||.|...|||:|:.:|.|...||.|.||.  .|.
  Fly   366 VNTTGADFVSSATTETEAEARQASLGPRGYVGLVNQAMTCYLNSLLQALFMTPEFRNALYRWEFD 430

  Fly   137 NDGTDTMSTAFSISSAMKSIFAQMEKGTTVTPIVLLQALHRASPQFA--------QTGENGT--Y 191
            ||     :.|.:|...::.:|..::                .||:.|        ..|.:.|  :
  Fly   431 ND-----NEAKNIPYQLQKLFLNLQ----------------TSPKAAVETTDLTRSFGWDSTEAW 474

  Fly   192 RQQDANECWAEILKMLQQKLRPKNQE------------------PSNTVQKRHSSFID-----QF 233
            :|.|..|....:...|:.|.:...|.                  ..||.:.|..:|:|     :.
  Fly   475 QQHDIQELCRVMFDALEHKFKNTKQANLISNLYEGKMNDYVKCLECNTEKTREDTFLDIPLPVRP 539

  Fly   234 FG-----GTFEVKMSSEEDPDEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSETLG 293
            ||     |:.|..:.:..   :|.|:...|  |..|                  |:..||.:  .
  Fly   540 FGSSSAYGSIEEALRAFV---QPETLDGNN--QYLC------------------EKCKKKCD--A 579

  Fly   294 RDAKYIRTYLVSRLPAYLTVQFVRFQYKGKEGINAKVLKDIKFP--IDFDAF---ELCTPELQNK 353
            ....:.:::     |..||:...||.:..:.....|:...:.||  ::.:.|   ...:.|..::
  Fly   580 HKGLHFKSF-----PYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLNLNTFINRSGNSGEQNSQ 639

  Fly   354 L------CPMRSKFKDLEDKKMEVDVVKRNEPNEEKKDVKYEQFWFDDDLGSNNSG-------YY 405
            |      |........:||..:...||.....::.:.|:..|....|....::.|.       .|
  Fly   640 LNGTVDDCSTADSGSAMEDDNLSSGVVTTASSSQHENDLNDEDEGIDMSSSTSKSAKQGSGPYLY 704

  Fly   406 TLQAVLTHKGRSSSSGHYVAWVRS-SGDVWFKFDDDEVSAVATDEILRLSGG--GDWHC------ 461
            .|.|::.|.| |:|.|||.|:::. ..:.||.|:|..|:::..::|.|..||  |.::.      
  Fly   705 ELFAIMIHSG-SASGGHYYAYIKDFDNNEWFCFNDQNVTSITQEDIQRSFGGPNGSYYSSAYTSS 768

  Fly   462 --AYVLLY 467
              ||:|:|
  Fly   769 TNAYMLMY 776

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Usp14NP_609377.1 Ubl_USP14_like 4..75 CDD:340521
Peptidase_C19A 105..467 CDD:239122 92/430 (21%)
Usp47NP_523937.2 DUF4045 <122..249 CDD:433066
peptidase_C19C 394..780 CDD:239124 93/435 (21%)
USP47_C 1300..1534 CDD:466158
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.