Protein Alignment Usp14 and usp14

DIOPT Version :10

• Sequence 1: NP_609377.1
• Gene: Usp14 / 34387
• FlyBaseID: FBgn0032216
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_956267.1
• Gene: usp14 / 335736
• ZFINID: ZDB-GENE-030131-7676
• Length: 489
• Species: Danio rerio
• Alignment Length: 492
• Identity: 273/492 - (55%)
• Similarity: 359/492 - (72%)
• Gaps: 21/492 - (4%)

  Fly     1 MPAFKVKVKWGRELYTDIVVNTDEEPILFKAQLFALTGVQPDRQKVMCKGGILKDDQW-NLQIKD 64
            ||.|.|.||||:|.:..:.:||:|.|::|||||||||||||:|||||.|||.||||:| |:::|:
Zfish     1 MPVFTVNVKWGKEKFDAVELNTEEPPMVFKAQLFALTGVQPERQKVMVKGGTLKDDEWGNIKLKN 65

  Fly    65 GAVVLLLGSKESVPEVPATPVKFIEDMNEAEAATAMRLPAGLTNLGNTCYMNATVQCLNAVPELR 129
            |..:|::||.:::||.|.....|:|||.|.:.|:||.||.||||||||||||||||||.:||||:
Zfish    66 GMTLLMMGSADALPEEPVVRPMFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCLRSVPELK 130

  Fly   130 TALSTFSNDGTDTMSTAFS--ISSAMKSIFAQMEK-GTTVTPIVLLQALHRASPQFAQTGENGTY 191
            .||..:|.....:.:.|.|  |::|::.::..|:| .:::.||:|||.||.|.||||:.|:.|.|
Zfish   131 GALRRYSGALRSSGANAPSQYITAALRDLYESMDKTSSSIPPIILLQFLHMAFPQFAEKGDQGQY 195

  Fly   192 RQQDANECWAEILKMLQQKLRPKNQEPSNTVQ----------KRHSSFIDQFFGGTFEVKMSSEE 246
            .||||||||.:::::|||||.|  |||...::          .:..|||||:||..||..|...|
Zfish   196 LQQDANECWVQVMRVLQQKLEP--QEPETPMETDGDSAAAASTKKKSFIDQYFGVEFETSMKCTE 258

  Fly   247 DPDEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSETLGRDAKYIRTYLVSRLPAYL 311
            ..||..|..:|:.|||||||:.:|||:.:||:.:::|.:.|.|.:|.|:|.||::..:||||||.
Zfish   259 AEDEEPTKGTESQLQLSCFINQEVKYLATGLRLRLQEDITKFSPSLQRNALYIKSSKISRLPAYH 323

  Fly   312 TVQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPELQNKLCPMRSKFKDLEDKKMEVDVVKR 376
            |||.|||.||.||.:|||||||:|||:..|.:||||.|||.|:..:|||||::||||:|..  ::
Zfish   324 TVQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTSELQEKMVSLRSKFKEMEDKKLEKQ--QK 386

  Fly   377 NEPNEEK---KDVKYEQFWFDDDLGSNNSGYYTLQAVLTHKGRSSSSGHYVAWVRSSGDVWFKFD 438
            :|||::.   |:.|||.|.|.|||||||||||.|||||||:|||||||||||||:...|.|.|||
Zfish   387 SEPNKKPGALKETKYEPFSFPDDLGSNNSGYYELQAVLTHQGRSSSSGHYVAWVKRKEDEWVKFD 451

  Fly   439 DDEVSAVATDEILRLSGGGDWHCAYVLLYAPRRLEKL 475
            ||:||.|..::||:||||||||.||||||.|||||.|
Zfish   452 DDKVSVVTPEDILKLSGGGDWHIAYVLLYGPRRLEML 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp14	NP_609377.1	Ubl_USP14_like	4..75	CDD:340521	43/71 (61%)
		Peptidase_C19A	105..467	CDD:239122	207/377 (55%)
usp14	NP_956267.1	Ubl_USP14_like	3..76	CDD:340521	43/72 (60%)
		Peptidase_C19A	106..481	CDD:239122	208/378 (55%)