Protein Alignment Usp14 and Usp14

DIOPT Version :10

• Sequence 1: NP_609377.1
• Gene: Usp14 / 34387
• FlyBaseID: FBgn0032216
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001008302.1
• Gene: Usp14 / 291796
• RGDID: 1311825
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 271/486 - (55%)
• Similarity: 350/486 - (72%)
• Gaps: 14/486 - (2%)

  Fly     1 MPAFKVKVKWGRELYTDIVVNTDEEPILFKAQLFALTGVQPDRQKVMCKGGILKDDQW-NLQIKD 64
            ||.:.|.||||:|.:..:.:||||.|::|||||||||||||.|||||.|||.||||.| |:::|:
  Rat     1 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKMKN 65

  Fly    65 GAVVLLLGSKESVPEVPATPVKFIEDMNEAEAATAMRLPAGLTNLGNTCYMNATVQCLNAVPELR 129
            |..||::||.:::||.|:....|:|||.|.:.||||.||.|||||||||||||||||:.:||||:
  Rat    66 GMTVLMMGSADALPEEPSAKTVFVEDMTEEQLATAMELPCGLTNLGNTCYMNATVQCIRSVPELK 130

  Fly   130 TALSTFSN--DGTDTMSTAFSISSAMKSIFAQMEK-GTTVTPIVLLQALHRASPQFAQTGENGTY 191
            .||..::.  ..:..|::|..|::|::.:|..|:| .:::.||:|||.||.|.||||:.||.|.|
  Rat   131 DALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQY 195

  Fly   192 RQQDANECWAEILKMLQQKL---------RPKNQEPSNTVQKRHSSFIDQFFGGTFEVKMSSEED 247
            .||||||||.:::::|||||         ..::...|.....:..|.||||||..||..|...|.
  Rat   196 LQQDANECWIQMMRVLQQKLEAIEDDSARETESSSASAVTPSKKKSLIDQFFGVEFETTMKCTES 260

  Fly   248 PDEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSETLGRDAKYIRTYLVSRLPAYLT 312
            .:|..|...||.|||||||:.:|||:.:|||.:::|::.|:|.||.|:|.||::..:||||||||
  Rat   261 EEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLT 325

  Fly   313 VQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPELQNKLCPMRSKFKDLEDKKMEVDVVKRN 377
            :|.|||.||.||.:|||||||:|||:..|.:||||||||.|:...|||||||||||:. .....|
  Rat   326 IQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMISFRSKFKDLEDKKVN-QQPNAN 389

  Fly   378 EPNEEKKDVKYEQFWFDDDLGSNNSGYYTLQAVLTHKGRSSSSGHYVAWVRSSGDVWFKFDDDEV 442
            :.|...|::|||.|.|.||:||||.|||.|||||||:||||||||||:||:...|.|.|||||:|
  Rat   390 DKNSPPKEIKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKEDEWIKFDDDKV 454

  Fly   443 SAVATDEILRLSGGGDWHCAYVLLYAPRRLE 473
            |.|..::|||||||||||.||||||.|||:|
  Rat   455 SIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp14	NP_609377.1	Ubl_USP14_like	4..75	CDD:340521	44/71 (62%)
		Peptidase_C19A	105..467	CDD:239122	205/373 (55%)
Usp14	NP_001008302.1	Ubl_USP14_like	4..76	CDD:340521	44/72 (61%)
		Peptidase_C19A	106..480	CDD:239122	210/380 (55%)