Protein Alignment Usp14 and usp-14

DIOPT Version :10

• Sequence 1: NP_609377.1
• Gene: Usp14 / 34387
• FlyBaseID: FBgn0032216
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_497006.1
• Gene: usp-14 / 175105
• WormBaseID: WBGene00006856
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 192/492 - (39%)
• Similarity: 276/492 - (56%)
• Gaps: 48/492 - (9%)

  Fly     1 MPAFKVKVKWGRELYTDIVVNTDEEPILFKAQLFALTGVQPDRQKVMCKGGILKDDQW-NLQIKD 64
            ||.  |.|||.:|.|. :.|:|...|::|||||||||.|.|:||||:..|..|.||.| .:.||:
 Worm     1 MPI--VNVKWQKEKYV-VEVDTSAPPMVFKAQLFALTQVVPERQKVVIMGRTLGDDDWEGITIKE 62

  Fly    65 GAVVLLLGSKESVPEVPATPVKFIEDMN---EAEAATAMRLPAGLTNLGNTCYMNATVQCLNAVP 126
            ...::::||...:|:.|....|  :..|   :||..:|: .|.||.|||||||.|:.||.|..|.
 Worm    63 NMTIMMMGSVGEIPKPPTVLEK--KQANRDKQAEEISAL-YPCGLANLGNTCYFNSCVQMLKEVN 124

  Fly   127 E--LRTALSTFSNDGTD----TMSTAFSISSAMKSIFAQMEKGTTVTPIVLLQALHRASPQFAQT 185
            |  |:.|......:..|    .::|.|  :|......|...||..:.|...:..|..:.|||.:
 Worm   125 ELVLKPAEEMRIREHNDRLCHNLATLF--NSLRDKDRALRSKGEPIKPFAAILTLSDSFPQFEK- 186

  Fly   186 GENGTYRQQDANECWAEILKMLQQKLRPKNQEPSNTVQKRHSS--FIDQFFGGTFEVKMSSEEDP 248
                 ::|||||||...|:              ||..:....|  .|:..|....|..|...|.
 Worm   187 -----FKQQDANECLVSIM--------------SNVTRIYGLSGWNIESLFRIQTETTMKCLES- 231

  Fly   249 DEPSTVTSENFLQLSCFISMDVKYMQSGLKSKMKEQLVKKSETLGRDAKYIRTYLVSRLPAYLTV 313
            ||.|....|...||:|:::.||:::|:|:|:..:|::.:.||.|.||||:.:...:||||.||||
 Worm   232 DEVSEKKVERNNQLTCYVNQDVRFLQTGIKAGFEEEMTRNSEELNRDAKWQKNTQISRLPKYLTV 296

  Fly   314 QFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPELQNKLCPMRSKFKDLEDKKMEVDVVKRNE 378
            ...||.||.....|||:||.::||:..|.::||:.||::||...|:..|..||.|:|.: :::..
 Worm   297 NINRFFYKESTKTNAKILKSVQFPMQLDTYDLCSQELKDKLVARRADIKLEEDAKLERE-LRKKV 360

  Fly   379 PNEEKKDVKYEQ-----FWFDDDLGSNNSGYYTLQAVLTHKGRSSSSGHYVAWVRSSGD-VWFKF 437
            .::|:.|..::.     ..|:||.||||||:|.|:.::|||||||..||||||:|||.| .|..|
 Worm   361 LDKEQGDKIFDDGVALPTAFEDDAGSNNSGFYDLKGIITHKGRSSQDGHYVAWMRSSEDGKWRLF 425

  Fly   438 DDDEVSAVATDEILRLSGGGDWHCAYVLLYAPRRLEK 474
            ||:.|:.|..:.||:.|||||||.||||||..|.:::
 Worm   426 DDEHVTVVDEEAILKTSGGGDWHSAYVLLYEARVIKQ 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp14	NP_609377.1	Ubl_USP14_like	4..75	CDD:340521	33/71 (46%)
		Peptidase_C19A	105..467	CDD:239122	146/375 (39%)
usp-14	NP_497006.1	Ubl_USP14_like	1..73	CDD:340521	35/74 (47%)
		Peptidase_C19A	103..456	CDD:239122	147/376 (39%)