Protein Alignment Cdk5alpha and cdk5r2

DIOPT Version :10

• Sequence 1: NP_523535.2
• Gene: Cdk5alpha / 34385
• FlyBaseID: FBgn0027491
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001072258.1
• Gene: cdk5r2 / 779711
• XenbaseID: XB-GENE-921924
• Length: 321
• Species: Xenopus tropicalis
• Alignment Length: 340
• Identity: 137/340 - (40%)
• Similarity: 178/340 - (52%)
• Gaps: 80/340 - (23%)

  Fly   127 SSFEKNLKKHSIFINALSWKKLSTSHNKKKIENKNKCANLPTACFKAQLLESSFASSSDKNRNIQ 191
            |..||:||:||:.|:||:||:|..:..|||  |..|.
 Frog    42 SKSEKSLKRHSVLISALTWKRLVAASAKKK--NAKKI---------------------------- 76

  Fly   192 LHCNRIDEHNQQHCNQHPHPHPHQHQLQLQNQHQ-HQNQNQNQNQNQVQDIREE-----VMTGPP 250
                            :|:|.|....|...|.:. .|..::|..::||...|.|     |.|.||
 Frog    77 ----------------NPNPGPINGPLLPNNNNPVEQLNHENLRKSQVSPGRREPKPVPVPTVPP 125

  Fly   251 GKSQNPSKAKDPVKVNNKNSMSNHNKLIQKQPLTLSLPQQVQASSIQTKNTNQIPRKTVIQASTS 315
            |.|:.             ..|.:....:|||....||..               ||:.::||||.
 Frog   126 GSSEG-------------QKMQHQLVAVQKQASGRSLCS---------------PRRVIVQASTG 162

  Fly   316 ELLKCLGMFLHCRCQRLNNFDAGDAVMWLRAVDRSLLLQGWQDVAFINPANVVFVYMLVRELVSG 380
            |||:|||.|:..||.||.....|:..||.|.|||:||||||||..||.|||:||||:|.||.:..
 Frog   163 ELLRCLGEFVCRRCYRLKELSPGELTMWFRNVDRALLLQGWQDQGFITPANLVFVYLLCREAIGD 227

  Fly   381 EESKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEKFWDRCLVIVNKLSDKMLKINAEP 445
            |.:.|.:|||..||||||:||||||||||||||||||..||.||.|||.|::::|.|||:||::|
 Frog   228 ELATEFELQACFLTCLYLAYSYMGNEISYPLKPFLVETDKEVFWQRCLSIIDRMSAKMLQINSDP 292

  Fly   446 GFFTEVFTELKSCGQ 460
            .|||:||.:||:.|:
 Frog   293 HFFTQVFQDLKNEGE 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5alpha	NP_523535.2	CDK5_activator	96..461	CDD:460866	137/340 (40%)
cdk5r2	NP_001072258.1	CDK5_activator	42..308	CDD:460866	137/340 (40%)