Protein Alignment Cdk5alpha and si:dkeyp-92c9.2

DIOPT Version :9

• Sequence 1: NP_001260320.1
• Gene: Cdk5alpha / 34385
• FlyBaseID: FBgn0027491
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001038685.1
• Gene: si:dkeyp-92c9.2 / 571482
• ZFINID: ZDB-GENE-060503-468
• Length: 317
• Species: Danio rerio
• Alignment Length: 473
• Identity: 161/473 - (34%)
• Similarity: 197/473 - (41%)
• Gaps: 183/473 - (38%)

  Fly     1 MGTVLSFNPRDRHPIYSSQPNFQYNHSTDMRNENDSTGSIDSHLNNFSYEQLNNAKNRENKKSAC 65
            ||||||.:|..|.|.|                .:|..||: ||..:.|...||..|:|..|:.
Zfish     1 MGTVLSLSPGPRKPGY----------------YDDRPGSL-SHYPSLSSRSLNTQKDRSLKRG-- 46

  Fly    66 HPMAKNVIGQPGGQCGGVHINLQTQTQLSSHNLNNLANASKDTITNVLDTHNENSVLKAEKSSFE 130
                                                                             
Zfish    47 ----------------------------------------------------------------- 46

  Fly   131 KNLKKHSIFINALSWKKLSTSHNKKKIENKNKCANLPTACFKAQLLESSFASSSDKNRNIQLHCN 195
                 ||||:.||:||:|..| .||:.|:|           ||.........:...|.||.
Zfish    47 -----HSIFLPALTWKRLVAS-TKKRGESK-----------KAYPGGQGAVGAPLNNNNIY---- 90

  Fly   196 RIDEHNQQHCNQHPHPHPHQHQLQLQNQHQHQNQNQNQNQNQVQDIREEVMTGPPGKSQNPSKAK 260
                                                                           .|
Zfish    91 ---------------------------------------------------------------QK 92

  Fly   261 DPV----KVNNKNSMSNHNKLIQKQPLTL---------SLPQQVQASSIQTKNTNQIPRKTVIQA 312
            ||:    :.|.|.|:|..|......|..:         .|||......|....|:. |::.::||
Zfish    93 DPILHLNRENVKKSLSCANLSSYDGPAGVGLGVGLGYGKLPQISSVKKIAPTCTSS-PKRVIVQA 156

  Fly   313 STSELLKCLGMFLHCRCQRLNNFDAGDAVMWLRAVDRSLLLQGWQDVAFINPANVVFVYMLVREL 377
            ||||||:|||.||..||.||.:....|.|:||||||||||||||||.||:.||||||||||.|::
Zfish   157 STSELLRCLGEFLCTRCYRLKHLSPADPVLWLRAVDRSLLLQGWQDQAFVTPANVVFVYMLCRDV 221

  Fly   378 VSGEE-SKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEKFWDRCLVIVNKLSDKMLKI 441
            |.|:. |.|.:|||.:|||||||||||||||||||||||||..||.||||||.|::..|.|||:|
Zfish   222 VDGDSVSSEHELQAILLTCLYLSYSYMGNEISYPLKPFLVEAGKEAFWDRCLAIIDVTSAKMLRI 286

  Fly   442 NAEPGFFTEVFTELKSCG 459
            ||:|.|||:||.:|||.|
Zfish   287 NADPHFFTQVFADLKSEG 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5alpha	NP_001260320.1	CDK5_activator	107..458	CDD:281279	138/364 (38%)
si:dkeyp-92c9.2	NP_001038685.1	CDK5_activator	40..302	CDD:281279	139/413 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593203
Domainoid	1	1.000	222	1.000	Domainoid score	I2518
eggNOG	1	0.900	-	-		E1_KOG3932
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3192
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492547at2759
OrthoFinder	1	1.000	-	-		FOG0001633
OrthoInspector	1	1.000	-	-		otm25117
orthoMCL	1	0.900	-	-		OOG6_107211
Panther	1	1.100	-	-	O	PTHR23401
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3652
SonicParanoid	1	1.000	-	-		X1362
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.790