Protein Alignment Cdk5alpha and cdk5r1b

DIOPT Version :10

• Sequence 1: NP_523535.2
• Gene: Cdk5alpha / 34385
• FlyBaseID: FBgn0027491
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001002515.2
• Gene: cdk5r1b / 436788
• ZFINID: ZDB-GENE-040718-220
• Length: 304
• Species: Danio rerio
• Alignment Length: 344
• Identity: 141/344 - (40%)
• Similarity: 190/344 - (55%)
• Gaps: 84/344 - (24%)

  Fly   120 SVLKAEKSSFEKNLKKHSIFINALSWKKLSTSHNKKKIENKNKCANLPTACFKAQLLESSFASSS 184
            :.::..|::.:||||:|.: ||.|.||::.....|||...|
Zfish    28 TAVQNSKNAKDKNLKRHPL-INVLPWKRIVAVSAKKKGSKK------------------------ 67

  Fly   185 DKNRNIQLHCNRIDEHNQQHCNQHPHPHPHQHQLQLQNQHQHQNQNQNQNQNQVQDIREEVMTGP 249
                   :..|...::|..|.|               |::..::|:.....:..||     .|.|
Zfish    68 -------VQPNTTYQNNVSHLN---------------NENLKKSQSCANLASFTQD-----QTSP 105

  Fly   250 PGKSQNPSKAKDPVKVNNKNSMSNHNKLIQKQPLTLSLPQQVQASSIQTKNTNQI---PRKTVIQ 311
               |...||       |:.|:.|:    ::|.||:               |:|.:   |::.::|
Zfish   106 ---SNQGSK-------NSNNTASS----VKKAPLS---------------NSNAVPGTPKRVIVQ 141

  Fly   312 ASTSELLKCLGMFLHCRCQRLNNFDAGDAVMWLRAVDRSLLLQGWQDVAFINPANVVFVYMLVRE 376
            |||||||:|||.||..||.||.:....|.|:|||:||||||||||||..||.||||||||||.|:
Zfish   142 ASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFVYMLCRD 206

  Fly   377 LVSGEESKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEKFWDRCLVIVNKLSDKMLKI 441
            :||.|.:.|.:|||.:|||||||||||||||||||||||||.|||.||||||.|:|.:|.|||:|
Zfish   207 VVSSEVATEHELQAVLLTCLYLSYSYMGNEISYPLKPFLVETSKETFWDRCLSIINLMSAKMLQI 271

  Fly   442 NAEPGFFTEVFTELKSCGQ 460
            |::|.:||:||.:||:..|
Zfish   272 NSDPHYFTQVFADLKNESQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5alpha	NP_523535.2	CDK5_activator	96..461	CDD:460866	141/344 (41%)
cdk5r1b	NP_001002515.2	CDK5_activator	20..291	CDD:460866	141/344 (41%)