Protein Alignment Cdk5alpha and cdk5r1b

DIOPT Version :9

• Sequence 1: NP_001260320.1
• Gene: Cdk5alpha / 34385
• FlyBaseID: FBgn0027491
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001002515.2
• Gene: cdk5r1b / 436788
• ZFINID: ZDB-GENE-040718-220
• Length: 304
• Species: Danio rerio
• Alignment Length: 344
• Identity: 141/344 - (40%)
• Similarity: 190/344 - (55%)
• Gaps: 84/344 - (24%)

  Fly   120 SVLKAEKSSFEKNLKKHSIFINALSWKKLSTSHNKKKIENKNKCANLPTACFKAQLLESSFASSS 184
            :.::..|::.:||||:|.: ||.|.||::.....|||...|
Zfish    28 TAVQNSKNAKDKNLKRHPL-INVLPWKRIVAVSAKKKGSKK------------------------ 67

  Fly   185 DKNRNIQLHCNRIDEHNQQHCNQHPHPHPHQHQLQLQNQHQHQNQNQNQNQNQVQDIREEVMTGP 249
                   :..|...::|..|.|               |::..::|:.....:..||     .|.|
Zfish    68 -------VQPNTTYQNNVSHLN---------------NENLKKSQSCANLASFTQD-----QTSP 105

  Fly   250 PGKSQNPSKAKDPVKVNNKNSMSNHNKLIQKQPLTLSLPQQVQASSIQTKNTNQI---PRKTVIQ 311
               |...||       |:.|:.|:    ::|.||:               |:|.:   |::.::|
Zfish   106 ---SNQGSK-------NSNNTASS----VKKAPLS---------------NSNAVPGTPKRVIVQ 141

  Fly   312 ASTSELLKCLGMFLHCRCQRLNNFDAGDAVMWLRAVDRSLLLQGWQDVAFINPANVVFVYMLVRE 376
            |||||||:|||.||..||.||.:....|.|:|||:||||||||||||..||.||||||||||.|:
Zfish   142 ASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFVYMLCRD 206

  Fly   377 LVSGEESKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEKFWDRCLVIVNKLSDKMLKI 441
            :||.|.:.|.:|||.:|||||||||||||||||||||||||.|||.||||||.|:|.:|.|||:|
Zfish   207 VVSSEVATEHELQAVLLTCLYLSYSYMGNEISYPLKPFLVETSKETFWDRCLSIINLMSAKMLQI 271

  Fly   442 NAEPGFFTEVFTELKSCGQ 460
            |::|.:||:||.:||:..|
Zfish   272 NSDPHYFTQVFADLKNESQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5alpha	NP_001260320.1	CDK5_activator	107..458	CDD:281279	140/340 (41%)
cdk5r1b	NP_001002515.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593202
Domainoid	1	1.000	222	1.000	Domainoid score	I2518
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3192
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492547at2759
OrthoFinder	1	1.000	-	-		FOG0001633
OrthoInspector	1	1.000	-	-		otm25117
orthoMCL	1	0.900	-	-		OOG6_107211
Panther	1	1.100	-	-	O	PTHR23401
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3652
SonicParanoid	1	1.000	-	-		X1362
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.890