Protein Alignment Cdk5alpha and cdka-1

DIOPT Version :10

• Sequence 1: NP_523535.2
• Gene: Cdk5alpha / 34385
• FlyBaseID: FBgn0027491
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001076650.1
• Gene: cdka-1 / 188812
• WormBaseID: WBGene00011955
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 361
• Identity: 121/361 - (33%)
• Similarity: 184/361 - (50%)
• Gaps: 70/361 - (19%)

  Fly   127 SSFEKNLKKHSIFINALSWKKLSTSHNKKKIENKNKCANLPTACFKAQLLESSFASSSDK----N 187
            ||...:..|.|:.:...:|       :|:.|:......:||.:   ....|::.:.|||.    .
 Worm    43 SSRSSSNAKESVLMQGWNW-------SKRNIQPVMSRRSLPKS---GSSSEATSSKSSDSLVSFT 97

  Fly   188 RNIQLHCN----RIDEHNQQHCNQHPHPHPHQHQLQLQNQHQHQNQNQNQNQNQVQDIREEVMTG 248
            ||:....:    :|.....::.|....|.|......:.|.:               .:|||...|
 Worm    98 RNVSTSTSSQYGKISISLDRNQNYKSVPRPSDTTTIIPNYY---------------SLREEFRRG 147

  Fly   249 PPGKSQNPSKAKDPVKVNNKNSMSNHNKLIQKQPLTLSLPQQV--QASSIQTKNTN--------- 302
                          :::|.:..:.|:| |.......:..|:.|  ..|.::..|.|
 Worm   148 --------------LQINTRQDLVNNN-LASNDLSVIGSPKHVPRPRSVLRDDNANCDISPIAEQ 197

  Fly   303 -QIP------RKTVIQASTSELLKCLGMFLHCRCQRLNNFDAGDAVMWLRAVDRSLLLQGWQDVA 360
             .:|      :||:|||||||||:.||:|:...|. :::||....|.|||:||||||||||||:|
 Worm   198 ENVPSEKRGTKKTIIQASTSELLRGLGIFISNNCD-VSDFDPAHLVTWLRSVDRSLLLQGWQDIA 261

  Fly   361 FINPANVVFVYMLVRELVSGEE---SKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEK 422
            ||||||:||:::|||:::..|.   ....:|.|.:|:|||:|||||||||||||||||:.:.:..
 Worm   262 FINPANLVFIFLLVRDVLPDERHLIHTLEELHAWILSCLYVSYSYMGNEISYPLKPFLIGNDRNT 326

  Fly   423 FWDRCLVIVNKLSDKMLKINAEPGFFTEVFTELKSC 458
            ||:||:.:|...|.:||.:|:...||:||||:||.|
 Worm   327 FWNRCVAMVTSHSRQMLLLNSSSTFFSEVFTDLKHC 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5alpha	NP_523535.2	CDK5_activator	96..461	CDD:460866	121/361 (34%)
cdka-1	NP_001076650.1	CDK5_activator	7..365	CDD:460866	121/361 (34%)