Protein Alignment Cdk5alpha and Cdk5r1

DIOPT Version :10

• Sequence 1: NP_523535.2
• Gene: Cdk5alpha / 34385
• FlyBaseID: FBgn0027491
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_446343.1
• Gene: Cdk5r1 / 116671
• RGDID: 629472
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 135/339 - (39%)
• Similarity: 184/339 - (54%)
• Gaps: 76/339 - (22%)

  Fly   120 SVLKAEKSSFEKNLKKHSIFINALSWKKLSTSHNKKKIENKNKCANLPTACFKAQLLESSFASSS 184
            :.::..|::.:||||:||| |:.|.||::.....|||...|.:    |.:.:     :|:.|..:
  Rat    28 TAVQNSKNAKDKNLKRHSI-ISVLPWKRIVAVSAKKKNSKKAQ----PNSSY-----QSNIAHLN 82

  Fly   185 DKNRNIQLHCNRIDEHNQQHCNQHPHPHPHQHQLQLQNQHQHQNQNQNQNQNQVQDIREEVMTG- 248
            ::|....|.|..:....|....|.|.|...|                              ::|
  Rat    83 NENLKKSLSCANLSTFAQPPPAQPPAPPASQ------------------------------LSGS 117

  Fly   249 PPGKSQNPSKAKDPVKVNNKNSMSNHNKLIQKQPLTLSLPQQVQASSIQTKNTNQIPRKTVIQAS 313
            ..|.|.:..||..|                                :|.:..|   |::.::|||
  Rat   118 QTGVSSSVKKAPHP--------------------------------AITSAGT---PKRVIVQAS 147

  Fly   314 TSELLKCLGMFLHCRCQRLNNFDAGDAVMWLRAVDRSLLLQGWQDVAFINPANVVFVYMLVRELV 378
            |||||:|||.||..||.||.:....|.|:|||:||||||||||||..||.||||||:|||.|:::
  Rat   148 TSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLYMLCRDVI 212

  Fly   379 SGEESKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEKFWDRCLVIVNKLSDKMLKINA 443
            |.|...:.:|||.:|||||||||||||||||||||||||..||.||||||.::|.:|.|||:|||
  Rat   213 SSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINA 277

  Fly   444 EPGFFTEVFTELKS 457
            :|.:||:||::||:
  Rat   278 DPHYFTQVFSDLKN 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5alpha	NP_523535.2	CDK5_activator	96..461	CDD:460866	135/339 (40%)
Cdk5r1	NP_446343.1	CDK5_activator	22..293	CDD:460866	135/339 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	97..133		11/97 (11%)