DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5390 and KLK6

DIOPT Version :9

Sequence 1:NP_001285802.1 Gene:CG5390 / 34383 FlyBaseID:FBgn0032213 Length:406 Species:Drosophila melanogaster
Sequence 2:NP_001012982.1 Gene:KLK6 / 5653 HGNCID:6367 Length:244 Species:Homo sapiens


Alignment Length:238 Identity:78/238 - (32%)
Similarity:116/238 - (48%) Gaps:39/238 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   165 AILREEGNLNLYECGGALIAPNVVLTAAHCVHNKQPSSIVVRAGEWDTQTQTEIRRHEDRYVKEI 229
            |.|...|:|   .|||.||.|..|||||||   |:| ::.|..|:.:.: |.|..:.:...|:.:
Human    37 AALYTSGHL---LCGGVLIHPLWVLTAAHC---KKP-NLQVFLGKHNLR-QRESSQEQSSVVRAV 93

  Fly   230 IYHEQFNKGSLYNDVAVMLLESPFTLQENIQTV-----CLPNVGDKFDFDRCYATGWGKNKFGKD 289
            | |..::..|...|:.::.|..|..|.|.||.:     |..|.      ..|:..||||.   .|
Human    94 I-HPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANT------TSCHILGWGKT---AD 148

  Fly   290 GEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAGGEK-DKDTCKGDGGSPLVCPIA 353
            |::...::...:.:|..::||    ....|:   :..:.:|||.|| .||:|:||.|.||||   
Human   149 GDFPDTIQCAYIHLVSREECE----HAYPGQ---ITQNMLCAGDEKYGKDSCQGDSGGPLVC--- 203

  Fly   354 GQKNRFKSAGIVAWG-IGCGEVNIPGVYASVAKLRPWIDAKLK 395
            |...|    |:|:|| |.||....||||.:|.:...||...::
Human   204 GDHLR----GLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5390NP_001285802.1 Tryp_SPc 153..391 CDD:238113 77/232 (33%)
Tryp_SPc 153..390 CDD:214473 76/231 (33%)
KLK6NP_001012982.1 Tryp_SPc 23..237 CDD:214473 76/231 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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