DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and masp2

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001116330.1	Gene:	masp2 / 560277	ZFINID:	ZDB-GENE-060130-154	Length:	684	Species:	Danio rerio

Alignment Length:	259	Identity:	76/259 - (29%)
Similarity:	123/259 - (47%)	Gaps:	29/259 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 KITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGA-LIAPNVVLTAAHCVHNKQPS-SIVVRAG 208
            |:.|..|  ||..|.||.:.|     .:.....||| |::...||||||.|.:.:.| ::.:|.|
Zfish   435 KVIGGEN--AEKNEIPWQVMI-----RMGTKFIGGASLLSDGWVLTAAHVVKSFEDSANLQLRMG 492

  Fly   209 EWDTQTQTEIRRHEDRYV----KEIIYHEQFNKGSL-YN-DVAVMLLESPFTLQENIQTVCLPNV 267
                    .::.|::..|    ::|..|.|::..:: :| |:|::.||....:.:.:..||||..
Zfish   493 --------TVKHHDNEAVVGIPQKIFIHPQYHHDNVNFNHDIALIKLEYKVPVSKAVMPVCLPGR 549

  Fly   268 GDKFDF---DRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGR-HFILHDSF 328
            .::|..   |....:|||.:.......:...||.|.:||.....|:|....|...: ..::.::.
Zfish   550 EERFVLKANDVGKVSGWGVSNINTPALFSGNLKYVHLPVSNFNDCKTKYDSTVTSKGKLVVTENM 614

  Fly   329 ICAG-GEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWID 391
            |||| .:..||:|:||.|.|........|:.| ..|||:||.||.:....|||..|:....||:
Zfish   615 ICAGFSQGGKDSCQGDSGGPFAFFDKQSKSWF-IGGIVSWGHGCAQAGYYGVYTKVSNYLSWIE 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	72/250 (29%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	71/249 (29%)
masp2	NP_001116330.1	CUB	24..130	CDD:214483
		EGF_CA	134..176	CDD:214542
		CUB	180..289	CDD:278839
		CCP	296..357	CDD:214478
		CCP	362..410	CDD:153056
		Tryp_SPc	435..676	CDD:214473	74/256 (29%)
		Tryp_SPc	436..679	CDD:238113	75/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910