DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and f10

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001015728.1	Gene:	f10 / 548445	XenbaseID:	XB-GENE-971433	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	353	Identity:	99/353 - (28%)
Similarity:	156/353 - (44%)	Gaps:	52/353 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 SSGSTGSENGGSS-STQYQSCGD---QKECVPRWLCANDTINTSGDGIIDIRLGTDAECKNYLDL 112
            ::|....|||.|. .|:..|||.   ::|.....|..||..|           .||::.:..::.
Frog   151 TNGYILGENGKSCLPTEKYSCGRRHMKRERRETKLHENDKKN-----------HTDSQNEVKMNQ 204

  Fly   113 CCDLPNKRKDPIFEFKPDHPEGCGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREEGNLNLYE 177
            ...||.:           :..|....|||....:|.|  .:|...||.||...::.:|..   ..
Frog   205 TGTLPER-----------NVTGINILNPNDPNVRIVG--GRECSQGECPWQALLVSDEDE---GF 253

  Fly   178 CGGALIAPNVVLTAAHCVHNKQPSSIVVRAGEWDTQTQ--TEIRRHEDRYVKEIIYHEQFNKGSL 240
            |||.:::...:||||||::..:...:||  ||.:|:..  || ..|:   |::||.|.:|.|.:.
Frog   254 CGGTILSREFILTAAHCMNQTKYFKVVV--GELNTKISEGTE-SIHK---VEKIIMHPRFVKSTY 312

  Fly   241 YNDVAVMLLESPFTLQENIQTVCLPN--VGDKFDFDRCYATGWGKNKFGKDGEYQVILKKVDMPV 303
            ..|:||:.|:......|||...|:|:  ..|:...:...|...|..:..:.|.....|:.:.:|.
Frog   313 DYDIAVIKLKEAINFTENIIPACIPDPEFADQVLMNEPDAMVSGFGRIHERGRQASTLQMLQVPY 377

  Fly   304 VPEQQCETNLRETRLGRHFILHDSFICAGGEKD-KDTCKGDGGSPLVCPIAGQKNRFKSAGIVAW 367
            :....|:.:       ..|.:.::..|||.:.: ||.|:||.|.|.|.|.   |..:...|||:|
Frog   378 IKRHSCKES-------STFAITENMFCAGFDTEVKDACQGDSGGPHVTPF---KGTYFVTGIVSW 432

  Fly   368 GIGCGEVNIPGVYASVAKLRPWIDAKLK 395
            |.||......|||..|:||..|:...||
Frog   433 GEGCARKGKFGVYTKVSKLHRWLKGVLK 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	73/242 (30%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	72/241 (30%)
f10	NP_001015728.1	GLA	22..84	CDD:214503
		EGF_CA	85..121	CDD:238011
		FXa_inhibition	128..163	CDD:373209	4/11 (36%)
		Tryp_SPc	228..456	CDD:238113	75/248 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000