DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and prss60.2

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	268	Identity:	95/268 - (35%)
Similarity:	139/268 - (51%)	Gaps:	32/268 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 CGYQNPNGVGFKITGAVNQEAEFGEFPWMLAIL--REEGNLNLYECGGALIAPNVVLTAAHCVHN 197
            || |.|  :..:|.|.||  |..|.:||.:::.  |..|:.    |||:||:...|||||||:..
Zfish    25 CG-QAP--LNSRIVGGVN--APEGSWPWQVSLQSPRYGGHF----CGGSLISSEWVLTAAHCLPG 80

  Fly   198 KQPSSIVVRAGEWDTQTQTEIRRHE-DRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQT 261
            ...||:||..|.   :||..:..|| .|.|.:||.|..:|..:..||:|::.|.|..|..:.|:.
Zfish    81 VSESSLVVYLGR---RTQQGVNTHETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRP 142

  Fly   262 VCLPNVGDKFDF-DRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILH 325
            |||......:.. ...:.||||..:.|.:.....||::..:|||...:|     ..:||...:.
Zfish   143 VCLAAQNSVYSAGTSSWITGWGDVQAGVNLPAPGILQETMIPVVANDRC-----NAQLGSGTVT- 201

  Fly   326 DSFICAGGEK-DKDTCKGDGGSPLV---CPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKL 386
            ::.||||..| .||||:||.|.|:|   |.:      :..|||.:||.||.:.|.||||..|::.
Zfish   202 NNMICAGLAKGGKDTCQGDSGGPMVTRLCTV------WIQAGITSWGYGCADPNSPGVYTRVSQY 260

  Fly   387 RPWIDAKL 394
            :.||.:|:
Zfish   261 QSWISSKI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	85/245 (35%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	84/244 (34%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	88/251 (35%)
		Tryp_SPc	34..267	CDD:238113	90/253 (36%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587376
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840