DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and masp2

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001011037.1	Gene:	masp2 / 496446	XenbaseID:	XB-GENE-1007491	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	411	Identity:	116/411 - (28%)
Similarity:	172/411 - (41%)	Gaps:	73/411 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MILLNCLVICLCIFSC---GAQDSSLDKLISDIFKTDETPKPSSPPPPVV---NPKDSSGSTGSE 59
            ::|.|...|.....:|   |..|..|.|.|                  :|   ||.|....|.|.
Frog   332 VLLENARTIPSFTMTCLPDGTWDKKLPKCI------------------IVNCGNPDDIENGTYSF 378

  Fly    60 NGGSSSTQYQSCGDQKECVPRWLCANDTINTSGDGIIDIRLGTDAECKNYLDLCCDLPNKRKDPI 124
            ......|.|.|       |.::.|........|.|  :.|.|.|...:       |:.:::|.|
Frog   379 VTAKEVTLYNS-------VVQYNCTEPYYIKEGKG--EYRCGADGFWE-------DIESEKKTP- 426

  Fly   125 FEFKPDHPEGCGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGALIAPNVVL 189
                |.....||.:.|...| :|.|  .:.|..|||||.:.|     |.|....||||:..|.:|
Frog   427 ----PICVPDCGKRKPAAAG-RIVG--GEFANVGEFPWQVFI-----NANNERGGGALLLDNWIL 479

  Fly   190 TAAHCVHNKQP-SSIVVRAGEWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPF 253
            ||||.|::... |||:::.|...||....||    .:.:.:..||.:..|...||:|::.|::..
Frog   480 TAAHVVYSYDDLSSILIKMGFLSTQDSNYIR----GWPEAVFIHEGYKPGHYNNDIALIKLKNKV 540

  Fly   254 TL-QENIQTVCLP------NVGDKFDFDRC-YATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCE 310
            .| :|:|..:|||      ::..|.|.:.. ...|||..:..:....   |:.|::.:|....|:
Frog   541 PLSEESILGICLPTKEKSYHISHKDDDNHVGLVAGWGLTEAQRSSRK---LRFVEVNIVDHSTCK 602

  Fly   311 TNLRETRLGRHFILHDSFICAGGEKD-KDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEV 374
            ...  .:|...:|:.::.||||.|.. ||:|.||.|..|....|..|..| ..|||:||:|||..
Frog   603 AEY--AKLDAQYIVTENMICAGFEIGVKDSCAGDSGGALAFMNAESKKWF-VGGIVSWGVGCGVA 664

  Fly   375 NIPGVYASVAKLRPWIDAKLK 395
            ...|||..|.....||:..::
Frog   665 RQYGVYTKVTNYLDWIEKTIQ 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	80/247 (32%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	79/246 (32%)
masp2	NP_001011037.1	CUB	30..139	CDD:238001
		FXa_inhibition	145..180	CDD:317114
		CUB	184..294	CDD:238001
		CCP	299..361	CDD:153056	8/28 (29%)
		CCP	365..430	CDD:153056	19/85 (22%)
		Tryp_SPc	443..680	CDD:214473	81/253 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910