DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP000411

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_001237291.3	Gene:	AgaP_AGAP000411 / 4576124	VectorBaseID:	AGAP000411	Length:	1091	Species:	Anopheles gambiae

Alignment Length:	279	Identity:	72/279 - (25%)
Similarity:	117/279 - (41%)	Gaps:	39/279 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 DHPEGCGYQNPNGVGFKITGAVNQEAE--FGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAA 192
            || ..||.:.     .|.|..::..|:  .|.:||..||..::.....|.|||:::....:|||:
Mosquito     8 DH-LSCGRRK-----VKTTYLIHNGADAIAGHWPWHAAIFHQKDKHKEYACGGSILDETTILTAS 66

  Fly   193 HCVHNK----QPSSIVVRAGEWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPF 253
            |||...    ..:.:.|..|:......:|..:..:  .:|||.:..|:|.|:.:|:|::.|.:..
Mosquito    67 HCVSTLSGVISAALVTVHVGQIHLNQSSEYTQTFE--AREIIINPGFSKASIIHDIALIKLRTNI 129

  Fly   254 TLQENIQTVCLPNVGDKFDFDRCYATGWGKN----KFGKDGEYQVI---LKKVDMPVVPEQQCET 311
            ::...:|.|||      :..|.......|:|    .||. .|..|:   ||:..:.||....|..
Mosquito   130 SMNRYVQPVCL------WTMDSALELIVGRNGTIVGFGL-SERDVVSEQLKQATIGVVDPYTCIA 187

  Fly   312 NLRETRLGRHFILHDSFICAGGEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNI 376
            :.|.. .|.|..|  ...|..|:.....|.||.|..:...::|   |:...|:|::....|...:
Mosquito   188 SDRVV-YGTHLTL--EMFCGKGQNGVSACNGDSGGGMFFEVSG---RWFVRGLVSFTPARGSSGL 246

  Fly   377 PG-----VYASVAKLRPWI 390
            ..     ||..|||...||
Mosquito   247 CDPLKYTVYTDVAKYVEWI 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	66/256 (26%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	64/254 (25%)
AgaP_AGAP000411	XP_001237291.3	Tryp_SPc	23..267	CDD:238113	66/258 (26%)
		Tryp_SPc	25..265	CDD:214473	64/254 (25%)
		Tryp_SPc	308..>462	CDD:304450
		Trypsin	838..1069	CDD:278516
		Tryp_SPc	864..>946	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910