DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5390 and prss36

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001005710.1	Gene:	prss36 / 448231	XenbaseID:	XB-GENE-5892976	Length:	719	Species:	Xenopus tropicalis

Alignment Length:	375	Identity:	113/375 - (30%)
Similarity:	160/375 - (42%)	Gaps:	68/375 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 TPKPSSPPPPVVNPKDSSGSTGSENGGSSSTQYQSCGDQKECVPRWLCANDTINTSGDGIIDIRL 100
            :|..|||.....:...||..|.|....||.|....             |:...::|...:....|
Frog   316 SPASSSPASSPASSPASSSPTSSSPASSSPTSSSP-------------ASSPASSSSTFVSPTIL 367

  Fly   101 GTDAECKNYLDLCCDLPNKRKDPIFEFKPDHPEGCGYQNPNGVGFKITGAVNQEAEFGEFPWMLA 165
            .|...                          |..||  :|. |..:|.|..  :|..|.:||.::
Frog   368 STTPA--------------------------PPACG--SPL-VSSRIVGGT--DAREGAWPWQVS 401

  Fly   166 ILREEGNLNLYECGGALIAPNVVLTAAHCVHNKQ-PSSIVVRAGEWD-TQTQ-TEIRRHEDRYVK 227
             ||..|:   :.|||::|....:||||||..|.| ||...||.|.:. .||. .||....||
Frog   402 -LRYRGS---HICGGSVIGTQWILTAAHCFENSQFPSDYEVRLGTYRLAQTSPNEITYTVDR--- 459

  Fly   228 EIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKF-DFDRCYATGWGKNKFGKDGE 291
             ||.:.||:..:|:.|:|::.|.||.|..:.|..||||:..:.| |...|:.||||......:..
Frog   460 -IIVNSQFDSSTLFGDIALIRLTSPITYTKYILPVCLPSTSNSFTDGMECWVTGWGTISLYVNLP 523

  Fly   292 YQVILKKVDMPVVPEQQCET--NLRETRLGRHFILHDSFIC----AGGEKDKDTCKGDGGSPLVC 350
            |...|::|..|::...:|:.  ::.........|:....||    |||   ||:||||.|.||||
Frog   524 YPKTLQEVMTPLINRTRCDQMYHIDSPVSASSEIIPSDQICSGYSAGG---KDSCKGDSGGPLVC 585

  Fly   351 PIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKLKIWSID 400
            .:.|   .:...|||:||.||.....||||..|.....|:.|:....::|
Frog   586 KLQG---IWYQIGIVSWGEGCAIAKRPGVYTLVPAYYSWVIAEENTVNVD 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	89/247 (36%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	88/246 (36%)
prss36	NP_001005710.1	Tryp_SPc	37..276	CDD:238113
prss36	NP_001005710.1	Tryp_SPc	385..622	CDD:238113	90/252 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000